The impact of disease comorbidities in Alzheimer's disease
JA Santiago, JA Potashkin - Frontiers in aging neuroscience, 2021 - frontiersin.org
A wide range of comorbid diseases is associated with Alzheimer's disease (AD), the most
common neurodegenerative disease worldwide. Evidence from clinical and molecular …
common neurodegenerative disease worldwide. Evidence from clinical and molecular …
Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury
M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …
an understanding of both the primary neurological injury and the secondary sequelae that …
A fiber-deprived diet causes cognitive impairment and hippocampal microglia-mediated synaptic loss through the gut microbiota and metabolites
Background Cognitive impairment, an increasing mental health issue, is a core feature of the
aging brain and neurodegenerative diseases. Industrialized nations especially, have …
aging brain and neurodegenerative diseases. Industrialized nations especially, have …
Neuroinflammation represents a common theme amongst genetic and environmental risk factors for Alzheimer and Parkinson diseases
RJ Boyd, D Avramopoulos, LL Jantzie… - Journal of …, 2022 - Springer
Multifactorial diseases are characterized by inter-individual variation in etiology, age of
onset, and penetrance. These diseases tend to be relatively common and arise from the …
onset, and penetrance. These diseases tend to be relatively common and arise from the …
The role of Lactobacillus in inflammatory bowel disease: from actualities to prospects
C Li, K Peng, S Xiao, Y Long, Q Yu - Cell Death Discovery, 2023 - nature.com
Abstract Inflammatory Bowel Disease (IBD), a chronic nonspecific intestinal inflammatory
disease, is comprised of Ulcerative Colitis (UC) and Crohn's Disease (CD). IBD is closely …
disease, is comprised of Ulcerative Colitis (UC) and Crohn's Disease (CD). IBD is closely …
What does disease progression look like in ulcerative colitis, and how might it be prevented?
NK Cleveland, J Torres, DT Rubin - Gastroenterology, 2022 - Elsevier
Ulcerative colitis (UC) has been characterized by inflammation limited to the mucosa.
Although sustained and durable remission has been associated with mucosal healing, the …
Although sustained and durable remission has been associated with mucosal healing, the …
Gut-derived β-amyloid: Likely a centerpiece of the gut–brain axis contributing to Alzheimer's pathogenesis
J Jin, Z Xu, L Zhang, C Zhang, X Zhao, Y Mao… - Gut …, 2023 - Taylor & Francis
Peripheral β-amyloid (Aβ), including those contained in the gut, may contribute to the
formation of Aβ plaques in the brain, and gut microbiota appears to exert an impact on …
formation of Aβ plaques in the brain, and gut microbiota appears to exert an impact on …
A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer's disease and gastrointestinal tract disorders
Consistent with the concept of the gut-brain phenomenon, observational studies suggest a
relationship between Alzheimer's disease (AD) and gastrointestinal tract (GIT) disorders; …
relationship between Alzheimer's disease (AD) and gastrointestinal tract (GIT) disorders; …
Mechanistic link between vitamin B12 and Alzheimer's disease
Alzheimer's disease (AD) is the most common form of dementia in the elderly population,
affecting over 55 million people worldwide. Histopathological hallmarks of this multifactorial …
affecting over 55 million people worldwide. Histopathological hallmarks of this multifactorial …
A meta-analysis investigating the relationship between inflammation in autoimmune disease, elevated CRP, and the risk of dementia
J Cooper, Y Pastorello, M Slevin - Frontiers in Immunology, 2023 - frontiersin.org
Alzheimer's Disease (AD) represents the most common type of dementia and is becoming a
steadily increasing challenge for health systems globally. Inflammation is developing as the …
steadily increasing challenge for health systems globally. Inflammation is developing as the …