Pediatric CNS tumors are the most common solid tumors of childhood and the second most
common cancer after hematological malignancies accounting for approximate 20 to 25% of …

Progresses over the past years have extensively improved our capacity to use genome-
scale analyses—including high-density genotyping and exome and genome sequencing …

Ependymal tumors across age groups are currently classified and graded solely by
histopathology. It is, however, commonly accepted that this classification scheme has limited …

Background Histopathological grading of ependymoma has been controversial with respect
to its reproducibility and clinical significance. In a 3-phase study, we reviewed the pathology …

To characterize the overall survival (OS) and cause specific survival (CSS), and variables
affecting outcome, in patients with primary spinal cord astrocytoma (SCA) and ependymoma …

No reliable classification is in clinical use for the therapeutic stratification of children with
ependymoma, such that disease risk might be identified and patients treated to ensure a …

Ependymomas in adults are rare and often misdiagnosed. This study reports on a series of
adult patients with confirmed ependymoma treated at The University of Texas MD Anderson …

Background: Despite previous research, prognostic factors for ependymoma remain
relatively controversial. The purpose of our study was to examine demographic, clinical, and …

Brain tumors, a group of heterogeneous diseases, are the second most common cancer and
the leading cause of cancer-related deaths in children. Insight into the prognosis of pediatric …

Background Mounting evidence supports the presence of heterogeneity in the presentation
of ependymoma patients with respect to location, histopathology, and behavior between …