Development of Nucleic‐Acid‐Based Electrochemical Biosensors for Clinical Applications

Z Zhang, P Sen, BR Adhikari, Y Li… - Angewandte …, 2022 - Wiley Online Library
Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …

Synthesis, secretion, function, metabolism and application of natriuretic peptides in heart failure

S Fu, P Ping, F Wang, L Luo - Journal of biological engineering, 2018 - Springer
As a family of hormones with pleiotropic effects, natriuretic peptide (NP) system includes
atrial NP (ANP), B-type NP (BNP), C-type NP (CNP), dendroaspis NP and urodilatin, with NP …

BNP/NT-proBNP in pulmonary arterial hypertension: time for point-of-care testing?

RA Lewis, C Durrington, R Condliffe… - European Respiratory …, 2020 - Eur Respiratory Soc
Despite the advent of new therapies and improved outcomes in patients with pulmonary
arterial hypertension (PAH), it remains a life-shortening disease and the time to diagnosis …

Brain natriuretic peptide and its biochemical, analytical, and clinical issues in heart failure: a narrative review

S Fu, P Ping, Q Zhu, P Ye, L Luo - Frontiers in physiology, 2018 - frontiersin.org
Heart failure (HF) is a primary cause of morbidity and mortality worldwide. As the most
widely studied and commonly applied natriuretic peptide (NP), B-type natriuretic peptide …

Recent advances in cardiac biomarkers detection: From commercial devices to emerging technologies

M Savonnet, T Rolland, M Cubizolles, Y Roupioz… - … of Pharmaceutical and …, 2021 - Elsevier
Although cardiac pathologies are the major cause of death in the world, it remains difficult to
provide a reliable diagnosis to prevent heart attacks. Rapid patient care and management in …

Photonic and electrochemical biosensors for near-patient tests–a critical comparison

TF Krauss, L Miller, C Wälti, S Johnson - Optica, 2024 - opg.optica.org
Research into diagnostic biosensors is a vibrant field that combines scientific challenge with
translational opportunities; innovation in healthcare is of great societal interest and is an …

State of the art of immunoassay methods for B-type natriuretic peptides: An update

A Clerico, M Franzini, S Masotti… - Critical Reviews in …, 2015 - Taylor & Francis
The aim of this review article is to give an update on the state of the art of the immunoassay
methods for the measurement of B-type natriuretic peptide (BNP) and its related peptides …

A systematic evaluation of immunoassay point-of-care testing to define impact on patients' outcomes

V Pecoraro, G Banfi, L Germagnoli… - Annals of clinical …, 2017 - journals.sagepub.com
Background Point-of-care testing has been developed to provide rapid test results. Most
published studies focus on analytical performance, neglecting its impact on patient …

Disproportionate mitral regurgitation determines survival in acute heart failure

M Berrill, I Beeton, D Fluck, I John… - Frontiers in …, 2021 - frontiersin.org
Objectives: To assess the prevalence and impact of mitral regurgitation (MR) on survival in
patients presenting to hospital in acute heart failure (AHF) using traditional …

Heart failure biomarkers at point-of-care: current utilization and future potential

ES Christenson, PO Collinson… - Expert Review of …, 2014 - Taylor & Francis
Heart failure (HF) is a prevalent disease that is associated with a high morbidity and
mortality; HF is estimated to cost the US healthcare system over US $39 billion annually …