Biochemical and mechanical regulation of actin dynamics
Polymerization of actin filaments against membranes produces force for numerous cellular
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …
Rho GTPase signaling in cancer progression and dissemination
E Crosas-Molist, R Samain… - Physiological …, 2022 - journals.physiology.org
Rho GTPases are a family of small G proteins that regulate a wide array of cellular
processes related to their key roles controlling the cytoskeleton. Cancer is a multistep …
processes related to their key roles controlling the cytoskeleton. Cancer is a multistep …
The actin cytoskeleton and actin-based motility
T Svitkina - Cold Spring Harbor perspectives in biology, 2018 - cshperspectives.cshlp.org
The actin cytoskeleton—a collection of actin filaments with their accessory and regulatory
proteins—is the primary force-generating machinery in the cell. It can produce pushing …
proteins—is the primary force-generating machinery in the cell. It can produce pushing …
Nucleation, stabilization, and disassembly of branched actin networks
AM Gautreau, FE Fregoso, G Simanov… - Trends in cell …, 2022 - cell.com
Arp2/3 complex is an actin filament nucleation and branching machinery conserved in all
eukaryotes from yeast to human. Arp2/3 complex branched networks generate pushing …
eukaryotes from yeast to human. Arp2/3 complex branched networks generate pushing …
The cytoskeleton—a complex interacting meshwork
T Hohmann, F Dehghani - Cells, 2019 - mdpi.com
The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …
Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and …
Y Zhao, L Bai, Y Zhang, R Yao, Y Sun, R Hang, X Chen… - Biomaterials, 2022 - Elsevier
Osseointegration of implants is a complex physiological process that requires temporal and
spatial regulation of immune responses, angiogenesis, and osteogenesis. To achieve …
spatial regulation of immune responses, angiogenesis, and osteogenesis. To achieve …
Actin dynamics, architecture, and mechanics in cell motility
L Blanchoin, R Boujemaa-Paterski… - Physiological …, 2014 - journals.physiology.org
Tight coupling between biochemical and mechanical properties of the actin cytoskeleton
drives a large range of cellular processes including polarity establishment, morphogenesis …
drives a large range of cellular processes including polarity establishment, morphogenesis …
The mammalian blood-testis barrier: its biology and regulation
DD Mruk, CY Cheng - Endocrine reviews, 2015 - academic.oup.com
Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …
Phase transitions of multivalent proteins can promote clustering of membrane receptors
Clustering of proteins into micrometer-sized structures at membranes is observed in many
signaling pathways. Most models of clustering are specific to particular systems, and …
signaling pathways. Most models of clustering are specific to particular systems, and …
Cell mechanics and the cytoskeleton
DA Fletcher, RD Mullins - Nature, 2010 - nature.com
The ability of a eukaryotic cell to resist deformation, to transport intracellular cargo and to
change shape during movement depends on the cytoskeleton, an interconnected network of …
change shape during movement depends on the cytoskeleton, an interconnected network of …