The heart in congenital diaphragmatic hernia: knowns, unknowns, and future priorities
N Patel, AC Massolo, US Kraemer… - Frontiers in …, 2022 - frontiersin.org
There is growing recognition that the heart is a key contributor to the pathophysiology of
congenital diaphragmatic hernia (CDH), in conjunction with developmental abnormalities of …
congenital diaphragmatic hernia (CDH), in conjunction with developmental abnormalities of …
The left ventricle in congenital diaphragmatic hernia: implications for the management of pulmonary hypertension
JP Kinsella, RH Steinhorn, MP Mullen… - The Journal of …, 2018 - jpeds.com
Congenital diaphragmatic hernia (CDH) is a complex syndrome that causes severe
hypoxemic respiratory failure and is associated with high mortality. CDH is characterized by …
hypoxemic respiratory failure and is associated with high mortality. CDH is characterized by …
Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia
C Luong, J Rey-Perra, A Vadivel, G Gilmour, Y Sauve… - Circulation, 2011 - Am Heart Assoc
Background—Lung hypoplasia and persistent pulmonary hypertension of the newborn limit
survival in congenital diaphragmatic hernia (CDH). Unlike other diseases resulting in …
survival in congenital diaphragmatic hernia (CDH). Unlike other diseases resulting in …
Current concepts on the pathogenesis and etiology of congenital diaphragmatic hernia
JJ Greer - Respiratory Physiology & Neurobiology, 2013 - Elsevier
This review outlines research that has advanced our understanding of the pathogenesis and
etiology of congenital diaphragmatic hernia (CDH). The majority of CDH cases involve …
etiology of congenital diaphragmatic hernia (CDH). The majority of CDH cases involve …
Pulmonary hypertension in congenital diaphragmatic hernia
H Mohseni-Bod, D Bohn - Seminars in pediatric surgery, 2007 - Elsevier
Clinically significant pulmonary hypertension (PHTN) is a common finding in newborn
infants with congenital diaphragmatic hernia (CDH) resulting in right to left shunting at pre …
infants with congenital diaphragmatic hernia (CDH) resulting in right to left shunting at pre …
Retinal dehydrogenase-2 is inhibited by compounds that induce congenital diaphragmatic hernias in rodents
J Mey, RP Babiuk, R Clugston, W Zhang… - The American journal of …, 2003 - Elsevier
Currently, the etiology of the serious developmental anomaly congenital diaphragmatic
hernia (CDH) is unknown. We have used an animal model of CDH to address this issue. We …
hernia (CDH) is unknown. We have used an animal model of CDH to address this issue. We …
Congenital diaphragmatic hernia: current status and review of the literature
AS de Buys Roessingh, AT Dinh-Xuan - European journal of pediatrics, 2009 - Springer
Abstract Treatment of congenital diaphragmatic hernia (CDH) challenges obstetricians,
pediatric surgeons, and neonatologists. Persistent pulmonary hypertension (PPHT) …
pediatric surgeons, and neonatologists. Persistent pulmonary hypertension (PPHT) …
Significance and outcome of left heart hypoplasia in fetal congenital diaphragmatic hernia
M Vogel, DB McElhinney, E Marcus… - … in Obstetrics and …, 2010 - Wiley Online Library
Objective In patients with a left‐sided congenital diaphragmatic hernia (CDH), the left
ventricle (LV) is often compressed and smaller than normal. The objective of this study was …
ventricle (LV) is often compressed and smaller than normal. The objective of this study was …
Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen
BR Noble, RP Babiuk, RD Clugston… - … of Physiology-Lung …, 2007 - journals.physiology.org
Congenital diaphragmatic hernia (CDH) is a developmental anomaly that results in
significant mortality and morbidity. The underlying etiology is poorly understood. Insights will …
significant mortality and morbidity. The underlying etiology is poorly understood. Insights will …
Congenital diaphragmatic hernia: antenatal prognostic factors: Does cardiac ventricular disproportion in utero predict outcome and pulmonary hypoplasia?
B Thebaud, A Azancot, P De Lagausie, E Vuillard… - Intensive care …, 1997 - Springer
Despite regular progress in neonatal intensive care, congenital diaphragmatic hernia (CDH)
diagnosed antenatally is still associated with up to 80% mortality. It is impossible to predict …
diagnosed antenatally is still associated with up to 80% mortality. It is impossible to predict …