Importance Crohn disease, a chronic gastrointestinal inflammatory disease, is increasing in
incidence and prevalence in many parts of the world. Uncontrolled inflammation leads to …

The emergence of data from clinical trials of biologics, the approval of new biologics, and
our improved understanding of psoriasis pathogenesis have increased the therapeutic …

Since the late 1990s, tumor necrosis factor alpha (TNF-α) inhibitors (anti-TNFs) have
revolutionized the therapy of immune-mediated inflammatory diseases (IMIDs) affecting the …

The burden of inflammatory bowel disease (IBD) in older adults (ie, aged over 60 years old)
is increasing due to a combination of an ageing population with compounding prevalence of …

Abstract Background and Aims The association between tumour necrosis factor inhibitors
[TNFi] and malignancy in patients with inflammatory bowel disease [IBD] is not well …

Abstract Purpose of the Review As treatment options for Inflammatory Bowel Disease (IBD)
expand each class of medication will have specific safety concerns and side-effect profiles …

Simple Summary Patients with inflammatory bowel disease (IBD) face an increased risk of
colorectal cancer, necessitating a surveillance program to detect early signs of cancer …

Rheumatoid arthritis (RA) management is driven by evidence, and new 2019 EULAR
recommendations help in refining the relevant place of different disease-modifying anti …

The recent approval of new medications with novel mechanisms of action and emergence of
updated safety information for existing therapies has changed the treatment landscape of …

Coronaviruses are non-segmented and single stranded positive-sense RNA (+ ssRNA)
viruses. To date, 06 human coronaviruses (HCoVs) are reported; α-CoVs (HCoVs-NL63 and …