Background X-linked adrenoleukodystrophy (X-ALD) is highly variable, ranging from slowly
progressive adrenomyeloneuropathy to severe brain demyelination and inflammation …

Males with X‐linked adrenoleukodystrophy (ALD) are at high risk for developing adrenal
insufficiency and/or progressive leukodystrophy (cerebral ALD) at an early age. Pathogenic …

X-linked adrenoleukodystrophy (XALD) is the most common leukodystrophy. It has an
estimated incidence of around 1/17.000, and a variable phenotype. Following the passage …

The advancements in population screening, including newborn screening, enables the
identification of disease-causing variants and timely initiation of treatment. However …

Microglial cells ensure essential roles in brain homeostasis. In pathological condition,
microglia adopt a common signature, called disease-associated microglial (DAM) signature …

X-linked adrenoleukodystrophy (X-ALD) is a neurodegenerative disease caused by
pathogenic variants in ABCD1 resulting in defective peroxisomal oxidation of very long …

Background X-linked adrenoleukodystrophy (ALD) is a neurometabolic disorder caused by
pathogenic variants in ABCD1 resulting very long-chain fatty acids (VLCFA) accumulation in …

Alcohol-related liver disease (ALD) presents a significant global health concern, with liver
transplantation being a crucial intervention for patients in the advanced stages of the …

Lipids play pivotal roles in an extensive range of metabolic and physiological processes. In
recent years, the convergence of trapped ion mobility (TIMS) and mass spectrometry (MS) …

Abstract Background Coronavirus disease 2019 (COVID-19) can not only infect the
respiratory system but also affect the nervous system through the release of inflammatory …