Lentiviral vectors: basic to translational
More than two decades have passed since genetically modified HIV was used for gene
delivery. Through continuous improvements these early marker gene-carrying HIVs have …
delivery. Through continuous improvements these early marker gene-carrying HIVs have …
Small ruminant lentivirus infections and diseases
E Minguijón, R Reina, M Pérez, L Polledo… - Veterinary …, 2015 - Elsevier
Small ruminant lentiviruses include viruses with diverse genotypes that frequently cross the
species barrier between sheep and goats and that display a great genetic variability. These …
species barrier between sheep and goats and that display a great genetic variability. These …
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
A Adachi, HE Gendelman, S Koenig, T Folks… - Journal of …, 1986 - Am Soc Microbiol
We constructed an infectious molecular clone of acquired immunodeficiency syndrome-
associated retrovirus. Upon transfection, this clone directed the production of infectious virus …
associated retrovirus. Upon transfection, this clone directed the production of infectious virus …
Isolation of a new human retrovirus from West African patients with AIDS
F Clavel, D Guétard, F Brun-Vézinet, S Chamaret… - Science, 1986 - science.org
The etiological agent of AIDS, LAV/HTLV-III, is common in Central Africa but is not endemic
in other areas of that continent. A novel human retrovirus, distinct from LAV/HTLV-III, has …
in other areas of that continent. A novel human retrovirus, distinct from LAV/HTLV-III, has …
Identification of four conserved motifs among the RNA‐dependent polymerase encoding elements.
Four consensus sequences are conserved with the same linear arrangement in RNA‐
dependent DNA polymerases encoded by retroid elements and in RNA‐dependent RNA …
dependent DNA polymerases encoded by retroid elements and in RNA‐dependent RNA …
The role of mononuclear phagocytes in HTLV-III/LAV infection
S Gartner, P Markovits, DM Markovitz, MH Kaplan… - Science, 1986 - science.org
Cells with properties characteristic of mononuclear phagocytes were evaluated for infectivity
with five different isolates of the AIDS virus, HTLV-III/LAV. Mononuclear phagocytes cultured …
with five different isolates of the AIDS virus, HTLV-III/LAV. Mononuclear phagocytes cultured …
Genome organization and transactivation of the human immunodeficiency virus type 2
M Guyader, M Emerman, P Sonigo, F Clavel… - Nature, 1987 - nature.com
Abstract Analysis of the nucleotide sequence of the human retrovirus associated with AIDS
in West Africa, HIV-2, shows that it is evolutionary distant from the previously characterized …
in West Africa, HIV-2, shows that it is evolutionary distant from the previously characterized …
Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic …
W Zhou, LJ Parent, JW Wills, MD Resh - Journal of virology, 1994 - Am Soc Microbiol
Retroviral Gag proteins are targeted to the plasma membrane, where they play the central
role in virion formation. Several studies have suggested that the membrane-binding signal is …
role in virion formation. Several studies have suggested that the membrane-binding signal is …
Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region
T Jacks, HD Madhani, FR Masiarz, HE Varmus - Cell, 1988 - Elsevier
The gag-pol protein of Rous sarcoma virus (RSV), the precursor to the enzymes responsible
for reverse transcription and integration, is expressed from two genes that lie in different …
for reverse transcription and integration, is expressed from two genes that lie in different …
A Novel Gene of HIV-1, vpu, and Its 16-Kilodalton Product
K Strebel, T Klimkait, MA Martin - Science, 1988 - science.org
A 16-kilodalton protein expressed in cells producing the human immunodeficiency virus
(HIV-1) was identified as the gene product of the vpu open reading frame. When expressed …
(HIV-1) was identified as the gene product of the vpu open reading frame. When expressed …