Lentiviral vectors: basic to translational

T Sakuma, MA Barry, Y Ikeda - Biochemical Journal, 2012 - portlandpress.com
More than two decades have passed since genetically modified HIV was used for gene
delivery. Through continuous improvements these early marker gene-carrying HIVs have …

Small ruminant lentivirus infections and diseases

E Minguijón, R Reina, M Pérez, L Polledo… - Veterinary …, 2015 - Elsevier
Small ruminant lentiviruses include viruses with diverse genotypes that frequently cross the
species barrier between sheep and goats and that display a great genetic variability. These …

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

A Adachi, HE Gendelman, S Koenig, T Folks… - Journal of …, 1986 - Am Soc Microbiol
We constructed an infectious molecular clone of acquired immunodeficiency syndrome-
associated retrovirus. Upon transfection, this clone directed the production of infectious virus …

Isolation of a new human retrovirus from West African patients with AIDS

F Clavel, D Guétard, F Brun-Vézinet, S Chamaret… - Science, 1986 - science.org
The etiological agent of AIDS, LAV/HTLV-III, is common in Central Africa but is not endemic
in other areas of that continent. A novel human retrovirus, distinct from LAV/HTLV-III, has …

Identification of four conserved motifs among the RNA‐dependent polymerase encoding elements.

O Poch, I Sauvaget, M Delarue, N Tordo - The EMBO journal, 1989 - embopress.org
Four consensus sequences are conserved with the same linear arrangement in RNA‐
dependent DNA polymerases encoded by retroid elements and in RNA‐dependent RNA …

The role of mononuclear phagocytes in HTLV-III/LAV infection

S Gartner, P Markovits, DM Markovitz, MH Kaplan… - Science, 1986 - science.org
Cells with properties characteristic of mononuclear phagocytes were evaluated for infectivity
with five different isolates of the AIDS virus, HTLV-III/LAV. Mononuclear phagocytes cultured …

Genome organization and transactivation of the human immunodeficiency virus type 2

M Guyader, M Emerman, P Sonigo, F Clavel… - Nature, 1987 - nature.com
Abstract Analysis of the nucleotide sequence of the human retrovirus associated with AIDS
in West Africa, HIV-2, shows that it is evolutionary distant from the previously characterized …

Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic …

W Zhou, LJ Parent, JW Wills, MD Resh - Journal of virology, 1994 - Am Soc Microbiol
Retroviral Gag proteins are targeted to the plasma membrane, where they play the central
role in virion formation. Several studies have suggested that the membrane-binding signal is …

Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region

T Jacks, HD Madhani, FR Masiarz, HE Varmus - Cell, 1988 - Elsevier
The gag-pol protein of Rous sarcoma virus (RSV), the precursor to the enzymes responsible
for reverse transcription and integration, is expressed from two genes that lie in different …

A Novel Gene of HIV-1, vpu, and Its 16-Kilodalton Product

K Strebel, T Klimkait, MA Martin - Science, 1988 - science.org
A 16-kilodalton protein expressed in cells producing the human immunodeficiency virus
(HIV-1) was identified as the gene product of the vpu open reading frame. When expressed …