Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and cognitive impairment. It is caused by synaptic failure and excessive …

Stem cell-based therapies for neurodegenerative diseases aim at halting clinical
deterioration by regeneration and by providing local support for damaged tissue …

The critical role of neuroinflammation in favoring and accelerating the pathogenic process in
Alzheimer's disease (AD) increased the need to target the cerebral innate immune cells as a …

Alzheimer's disease (AD) is characterized by the accumulation of β-amyloid peptide (Aβ) in
the brain because of an imbalance between Aβ production and clearance. Neprilysin (NEP) …

Alzheimer's disease (AD) is a disabling and highly prevalent neurodegenerative condition,
for which there are no effective therapies. Soluble oligomers of the amyloid-β peptide (AβOs) …

Introduction We conducted a phase 1 clinical trial in nine patients with mild‐to‐moderate
Alzheimer's disease to evaluate the safety and dose‐limiting toxicity of stereotactic brain …

Bone marrow Mesenchymal Stem Cells (BM-MSCs), due to their strong protective and anti-
inflammatory abilities, have been widely investigated in the context of several diseases for …

Recently, mesenchymal stromal cell (MSC)-based therapy has become an appreciated
therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a …

Alzheimer's disease (AD) is characterized by the accumulation of amyloid plaques and
neurofibrillary tangles accompanied by cognitive dysfunction. The aim of the present study …

In the recent times, stem cell biology has garnered the attention of the scientific fraternity and
the general public alike due to the immense therapeutic potential that it holds in the field of …