Ghrelin was discovered in 1999 as the endogenous ligand of the growth-hormone
secretagogue receptor 1a (GHSR1a). Since then, ghrelin has been found to exert a plethora …

Ghrelin is an octanoylated peptide that acts via its specific receptor, the growth hormone
secretagogue receptor type 1a (GHSR-1a), and regulates a vast variety of physiological …

There is a growing interest in modulating gut microbiota with diet in the context of obesity.
The purpose of the present study was to evaluate the dose-dependent effects of prebiotics …

Food intake is tightly regulated by homeostatic and reward mechanisms and the adequate
function of both is necessary for the proper maintenance of energy balance. Ghrelin impacts …

OBJECTIVE Bariatric surgery causes durable weight loss. Gut hormones are implicated in
obesity pathogenesis, dietary failure, and mediating gastrointestinal bypass (GIBP) surgery …

Epilepsy is a common neurological disorder characterized by recurrent seizures. These
seizures are due to abnormal excessive and synchronous neuronal activity in the brain …

The peripheral peptide hormone ghrelin is a powerful stimulator of food intake, which leads
to body weight gain and adiposity in both rodents and humans. The hormone, thus …

Aims/hypothesis Proinflammatory and proapoptotic cytokines such as TNF-α are
upregulated in human obesity. We evaluated the association between ghrelin isoforms …

Alzheimer's disease (AD) is a multifactorial progressive neurodegenerative disorder
characterized by loss of memory and cognitive deficits, strongly influenced by the metabolic …

Obesity is one of the major social and health problems globally and often associated with
various other pathological conditions. In addition to unregulated eating behaviour …