Mitochondria are not only central organelles in metabolism and energy conversion but are
also platforms for cellular signaling cascades. Classically, the shape and ultrastructure of …

Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Mitochondrial morphology varies tremendously across cell types and tissues, changing
rapidly in response to external insults and metabolic cues, such as nutrient status. The many …

The mitochondria is the major hub to convert energy for cellular processes. Dysregulation of
mitochondrial function is one of the classical hallmarks of aging, and mitochondrial …

Mitochondrial fission is necessary for the maintenance of the mitochondrial network, and
relies on the GTPase dynamin-related protein 1 (DRP1; also known as DNM1L, dynamin-1 …

Over the past decades, peroxisomes have emerged as key regulators in overall cellular lipid
and reactive oxygen species metabolism. In mammals, these organelles have also been …

Lipid exchange between the endoplasmic reticulum (ER) and peroxisomes is necessary for
the synthesis and catabolism of lipids, the trafficking of cholesterol, and peroxisome …

Mitochondria are organized in the cell in the form of a dynamic, interconnected network.
Mitochondrial dynamics, regulated by mitochondrial fission, fusion, and trafficking, ensure …

Peroxisomes (POs) and the endoplasmic reticulum (ER) cooperate in cellular lipid
metabolism and form tight structural associations, which were first observed in ultrastructural …

Mitochondria are essential organelles performing important cellular functions ranging from
bioenergetics and metabolism to apoptotic signaling and immune responses. They are …