Biomaterials and controlled release strategy for epithelial wound healing

YJ Son, WT John, Y Zhou, W Mao, EKF Yim… - Biomaterials …, 2019 - pubs.rsc.org
The skin and cornea are tissues that provide protective functions. Trauma and other
environmental threats often cause injuries, infections and damage to these tissues, where …

The multifaceted role of aquaporins in physiological cell migration

IM Smith, KM Stroka - American Journal of Physiology-Cell …, 2023 - journals.physiology.org
Cell migration is an essential process that underlies many physiological processes,
including the immune response, organogenesis in the embryo, and angiogenesis, as well as …

[HTML][HTML] Molecular characteristics and spatial distribution of adult human corneal cell subtypes

AJ Ligocki, W Fury, C Gutierrez, C Adler, T Yang… - Scientific reports, 2021 - nature.com
Bulk RNA sequencing of a tissue captures the gene expression profile from all cell types
combined. Single-cell RNA sequencing identifies discrete cell-signatures based on …

[HTML][HTML] The extracts of dendrobium alleviate dry eye disease in rat model by regulating aquaporin expression and MAPKs/NF-κB Signalling

J Ling, CL Chan, CY Ho, X Gao, SM Tsang… - International Journal of …, 2022 - mdpi.com
Dry eye is one of the most common ocular surface diseases caused by tear film instability
and ocular surface damage due to an abnormal quality or quantity of tears. Inflammatory …

[HTML][HTML] Aquaporin5 deficiency aggravates ROS/NLRP3 inflammasome-mediated pyroptosis in the lacrimal glands

X Cao, G Di, Y Bai, K Zhang, Y Wang… - … & Visual Science, 2023 - tvst.arvojournals.org
Purpose: The pathogenesis of the lacrimal glands (LGs) is facilitated by inflammation
mediated by the NACHT, LRR, and NLRP3 inflammasomes in dry eye disease. This …

[HTML][HTML] Expression profiles of CircRNA and mRNA in lacrimal glands of AQP5–/–mice with primary dry eye

Y Liu, G Di, S Hu, T Zhao, X Xu, X Wang… - Frontiers in …, 2020 - frontiersin.org
Purpose: This work aimed to identify differentially expressed circular RNAs (circRNAs) and
elucidate their potential function in aquaporin 5 (AQP5) knockout (AQP5–/–) mice with the …

[HTML][HTML] Aquaporin 5 facilitates corneal epithelial wound healing and nerve regeneration by reactivating Akt signaling pathway

Y Liu, G Di, Y Wang, D Chong, X Cao… - The American Journal of …, 2021 - Elsevier
Aquaporins (AQPs) are a highly conserved group of membrane proteins that play critical
roles in water and small solute transport across epithelial and endothelial barriers. The aim …

[HTML][HTML] Comprehensive analysis of aquaporin superfamily in lung adenocarcinoma

G Lin, L Chen, L Lin, H Lin, Z Guo, Y Xu… - Frontiers in molecular …, 2021 - frontiersin.org
Background: Lung adenocarcinoma (LUAD) is the most predomintnt lung cancer subtype
with increasing morbidity and mortality. Previous studies have shown that aquaporin (AQP) …

[HTML][HTML] Unexpected localization of AQP3 and AQP4 induced by migration of primary cultured IMCD cells

R Rose, B Kemper, A Schwab, E Schlatter… - Scientific Reports, 2021 - nature.com
Abstract Aquaporin-2–4 (AQP) are expressed in the principal cells of the renal collecting
duct (CD). Beside their role in water transport across membranes, several studies showed …

Role of aquaporins in corneal healing post chemical injury

ME Bhend, D Kempuraj, NR Sinha, S Gupta… - Experimental Eye …, 2023 - Elsevier
Aquaporins (AQPs) are transmembrane water channel proteins that regulate the movement
of water through the plasma membrane in various tissues including cornea. The cornea is …