For decades after the discovery that a contractile ring made of actin filaments and myosin II
produces the force to constrict the cleavage furrow of animal cells, the complexity of …

Anillin is a highly conserved multidomain protein that interacts with cytoskeletal components
as well as their regulators. Throughout phylogeny, Anillins contribute to cytokinesis, the cell …

Cell division facilitated by a contractile ring is an almost universal feature across all
branches of cellular life, with the notable exception of higher plants. In all organisms that use …

Cytokinesis in animals, fungi, and amoebas depends on the constriction of a contractile ring
built from a common set of conserved proteins. Many fundamental questions remain about …

The contractile ring is essential for cytokinesis in most fungal and animal cells. In fission
yeast, cytokinesis nodes are precursors of the contractile ring and mark the future cleavage …

Eukaryotic cells display a wide range of morphologies important for cellular function and
development. A particular cell shape is made via the generation of asymmetry in the …

The contractile ring is a complex molecular apparatus which physically divides many
eukaryotic cells. Despite knowledge of its protein composition, the molecular architecture of …

How the actin cytoskeleton assembles into different structures to drive diverse cellular
processes is a fundamental cell biological question. In addition to orchestrating the …

The septation initiation network (SIN) regulates aspects of cell growth and division in
Schizosaccharomyces pombe and is essential for cytokinesis. Insufficient signalling results …

Cytokinesis in Schizosaccharomyces pombe requires the function of Cdc15, the founding
member of the pombe cdc15 homology (PCH) family of proteins. As an early, abundant …