[HTML][HTML] New insights into the role of inflammation in the pathogenesis of atherosclerosis

MY Wu, CJ Li, MF Hou, PY Chu - International journal of molecular …, 2017 - mdpi.com
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of
lipids, smooth muscle cell proliferation, cell apoptosis, necrosis, fibrosis, and local …

[图书][B] An introduction to outlier analysis

CC Aggarwal, CC Aggarwal - 2017 - Springer
Outliers are also referred to as abnormalities, discordants, deviants, or anomalies in the data
mining and statistics literature. In most applications, the data is created by one or more …

[HTML][HTML] Vascular calcification: key roles of phosphate and pyrophosphate

R Villa-Bellosta - International Journal of Molecular Sciences, 2021 - mdpi.com
Cardiovascular complications due to accelerated arterial stiffening and atherosclerosis are
the leading cause of morbimortality in Western society. Both pathologies are frequently …

Cytokines in atherosclerosis: pathogenic and regulatory pathways

A Tedgui, Z Mallat - Physiological reviews, 2006 - journals.physiology.org
Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

Osteopontin in vascular disease: Friend or foe?

ZSY Lok, AN Lyle - Arteriosclerosis, thrombosis, and vascular …, 2019 - Am Heart Assoc
Inflammatory cytokines are necessary for an acute response to injury and the progressive
healing process. However, when this acute response does not resolve and becomes …

Phosphate regulation of vascular smooth muscle cell calcification

S Jono, MD McKee, CE Murry, A Shioi… - Circulation …, 2000 - Am Heart Assoc
Vascular calcification is a common finding in atherosclerosis and a serious problem in
diabetic and uremic patients. Because of the correlation of hyperphosphatemia and vascular …

[HTML][HTML] The role of osteopontin in inflammatory processes

SA Lund, CM Giachelli, M Scatena - Journal of cell communication and …, 2009 - Springer
Osteopontin (OPN) is a matricellular protein that mediates diverse biological functions. OPN
is involved in normal physiological processes and is implicated in the pathogenesis of a …

Vascular calcification: mechanisms and clinical ramifications

M Abedin, Y Tintut, LL Demer - Arteriosclerosis, thrombosis, and …, 2004 - Am Heart Assoc
Vascular calcification, long thought to result from passive degeneration, involves a complex,
regulated process of biomineralization resembling osteogenesis. Evidence indicates that …

Vascular calcification: the killer of patients with chronic kidney disease

M Mizobuchi, D Towler… - Journal of the American …, 2009 - journals.lww.com
Cardiovascular complications are the leading cause of death in patients with chronic kidney
disease (CKD). Vascular calcification is a common complication in CKD, and investigators …

Atherothrombosis and high-risk plaque: part I: evolving concepts

V Fuster, PR Moreno, ZA Fayad, R Corti… - Journal of the American …, 2005 - jacc.org
Atherothrombosis is a complex disease in which cholesterol deposition, inflammation, and
thrombus formation play a major role. Rupture of high-risk, vulnerable plaques is …