Update on infections caused by Stenotrophomonas maltophilia with particular attention to resistance mechanisms and therapeutic options

YT Chang, CY Lin, YH Chen, PR Hsueh - Frontiers in microbiology, 2015 - frontiersin.org
Stenotrophomonas maltophilia is a Gram-negative, biofilm-forming bacterium. Although
generally regarded as an organism of low virulence, S. maltophilia is an emerging multi …

Ventilator-associated pneumonia

J Chastre, JY Fagon - American journal of respiratory and critical …, 2002 - atsjournals.org
Ventilator-associated pneumonia (VAP) continues to complicate the course of 8 to 28% of
patients receiving mechanical ventilation (MV). In contrast to infections of more frequently …

Aminoglycoside Resistance in Pseudomonas aeruginosa

K Poole - Antimicrobial agents and Chemotherapy, 2005 - Am Soc Microbiol
Aminoglycosides (35) are a vital component of antipseudomonal chemotherapy implicated
in the treatment of a variety of infections (9, 45), particularly pulmonary infections in cystic …

Extended-spectrum β-lactamases: implications for the clinical microbiology laboratory, therapy, and infection control

E Stürenburg, D Mack - Journal of infection, 2003 - Elsevier
Extended-spectrum β-lactamase (ESBL) producing gram-negative bacilli are a growing
concern in human medicine today. When producing these enzymes, organisms (mostly K …

Prevention of resistance: a goal for dose selection for antimicrobial agents

GL Drusano - Clinical infectious diseases, 2003 - academic.oup.com
Drug-resistant microorganisms have become a major problem around the world. In
nosocomial and community settings, many important pathogens have demonstrated high …

Extended-spectrum β-lactamases and clinical outcomes: current data

R Ramphal, PGA > - Clinical infectious diseases, 2006 - academic.oup.com
Nosocomial infections caused by extended-spectrum β-lactamase (ESBL)—producing gram-
negative bacteria complicate therapy and limit treatment options. However, the clinical …

Antibiotics: where did we go wrong?

KM Overbye, JF Barrett - Drug discovery today, 2005 - Elsevier
In the late 1960s, the medical need for new antibiotics began to be questioned, and the
pharmaceutical industry shifted its emphasis of antibacterials from that of a therapeutic …

Antimicrobial resistance in Cairo, Egypt 1999–2000: a survey of five hospitals

A El Kholy, H Baseem, GS Hall… - Journal of …, 2003 - academic.oup.com
Antimicrobial resistance among bacterial pathogens is a global problem, but in Egypt data
are sparse. We reviewed the antimicrobial susceptibility patterns of bloodstream isolates of …

Global epidemiology of antimicrobial resistance among community-acquired and nosocomial pathogens: a five-year summary from the SENTRY Antimicrobial …

RN Jones - Seminars in respiratory and critical care medicine, 2003 - thieme-connect.com
Resistance to antimicrobial agents among clinically important pathogens in the community
and hospital settings has compromised therapy and requires constant monitoring of …

Quinupristin-dalfopristin and linezolid: evidence and opinion

LD Saravolatz, GM Eliopoulos - Clinical infectious diseases, 2003 - academic.oup.com
Quinupristin-dalfopristin and linezolid demonstrate in vitro activity against a wide range of
gram-positive bacteria, including many isolates resistant to earlier antimicrobials …