Opioid use kills tens of thousands of Americans each year, devastates families and entire
communities, and cripples the health care system. Exposure to opioids causes long-term …

A growing body of evidence from the past 15 years implicates epigenetic mechanisms in the
behavioral effects of addictive drugs. The main focus of these studies has been epigenetic …

Drug addiction involves long-term behavioral abnormalities that arise in response to
repeated exposure to drugs of abuse in vulnerable individuals. It is a multifactorial syndrome …

Chronic use of drugs of abuse results in neurochemical, morphological and behavioral
plasticity that underlies the emergence of compulsive drug seeking and vulnerability to …

Recent investigations have revealed that changes in DNA methylation status play an
important role in aging-associated pathologies and lifespan. The methylation of DNA is …

Decades of research on cocaine has produced volumes of data that have answered many
important questions about the nature of this highly addictive drug. Sadly, none of this …

Long processing cycle makes vacuum assisted resin infusion molding (VARIM) only suitable
for low and medium volumes of production, and shortening of curing time is critical to …

Early‐life stress (ES) impairs cognition later in life. Because ES prevention is problematic,
intervention is needed, yet the mechanisms that underlie ES remain largely unknown. So far …

Background Cocaine use disorder (CUD) is characterized by a loss of control over cocaine
intake and is associated with structural, functional, and molecular alterations in the human …

Drug addiction has been associated with an increased risk for cancer, psychological
complications, heart, liver, and lung disease, as well as infection. While genes have been …