Autoimmune and inflammatory mechanisms in atherosclerosis

G Wick, M Knoflach, Q Xu - Annu. Rev. Immunol., 2004 - annualreviews.org
The present review focuses on the concept that cellular and humoral immunity to the
phylogenetically highly conserved antigen heat shock protein 60 (HSP60) is the initiating …

Role of heat shock proteins in atherosclerosis

Q Xu - Arteriosclerosis, thrombosis, and vascular biology, 2002 - Am Heart Assoc
Heat shock proteins (HSPs) are present in most cells, serving as molecular chaperones, and
they play a role in cell protection from damage in response to stress stimuli. However …

Cross-reactive B-cell epitopes of microbial and human heat shock protein 60/65 in atherosclerosis

H Perschinka, M Mayr, G Millonig… - … , and vascular biology, 2003 - Am Heart Assoc
Objective—Growing evidence suggests that immune reactions to heat shock protein 60
(HSP60) are involved in atherogenesis. Because of the high phylogenetic conservation …

Atherosclerosis as an autoimmune disease: an update

G Wick, H Perschinka, G Millonig - TRENDS in Immunology, 2001 - cell.com
Immunoinflammatory processes are discussed increasingly as possible pathogenic factors
for the development of atherosclerosis. Here, we summarize the data on which we have built …

[HTML][HTML] Plasma levels of Hsp70 and anti-Hsp70 antibody predict risk of acute coronary syndrome

X Zhang, Z Xu, L Zhou, Y Chen, M He, L Cheng… - Cell Stress and …, 2010 - Elsevier
Although immune reactions against heat shock proteins have been implicated in the
pathogenesis of atherosclerosis, conflicting associations between Hsp70, anti-Hsp70 …

Immunological aspects of heat-shock proteins—the optimum stress of life

Z Prohászka, G Füst - Molecular immunology, 2004 - Elsevier
This review summarizes the complex role of heat-shock proteins (Hsp) in immune reactions,
especially the cellular effects of heat-shock proteins during the recognition processes by …

Hsp60 and heme oxygenase-1 (Hsp32) in acute myocardial infarction

G Novo, F Cappello, M Rizzo, G Fazio, S Zambuto… - Translational …, 2011 - Elsevier
Heat shock proteins (Hsps) are produced in response to various stressors, including
ischemia-reperfusion, and they can exit cells and reach the blood. In this pilot study, we …

A Review of the Postulated Mechanisms Concerning the Association of Helicobacter pylori with Ischemic Heart Disease

A Manolakis, AN Kapsoritakis, SP Potamianos - Helicobacter, 2007 - Wiley Online Library
Since its discovery, Helicobacter pylori has been implicated in the pathogenesis of several
diseases, both digestive and extradigestive. Interestingly, the majority of the extradigestive …

Helicobacter pylori Infection in Connective Tissue Disorders is Associated with High Levels of Antibodies to Mycobacterial hsp65 but not to Human hsp60

L Kalabay, B Fekete, L Czirják, L Horváth… - …, 2002 - Wiley Online Library
Background. To investigate whether the Helicobacter pylori status influences levels of
antibodies against mycobacterial heat shock protein (hsp) 65 and human hsp60 in systemic …

[HTML][HTML] H pylori infection and systemic antibodies to CagA and heat shock protein 60 in patients with coronary heart disease

C Lenzi, A Palazzuoli, N Giordano… - World Journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To determine the overall prevalence of H pylori and CagA positive H pylori infection
and the prevalence of other bacterial and viral causes of chronic infection in patients with …