Single-cell RNA sequencing (scRNA-seq) has allowed profiling cell types of the dorsal root
ganglia (DRG) and their transcriptional states in physiology and chronic pain. However, the …

Sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are
specialized to detect and transduce diverse environmental stimuli to the central nervous …

Appropriate regulation of the inflammatory response is essential for survival. Interleukin-10
(IL-10), a well-known anti-inflammatory cytokine, plays a major role in controlling …

Dorsal root ganglia (DRG) somatosensory neurons detect mechanical, thermal, and
chemical stimuli acting on the body. Achieving a holistic view of how different DRG neuron …

It has been presumed that rheumatoid arthritis (RA) joint pain is related to inflammation in
the synovium; however, recent studies reveal that pain scores in patients do not correlate …

Introduction Chronic itch is a central symptom of atopic dermatitis. Cutaneous afferent
neurons express receptors interleukins (IL)-4, IL-13, and IL-33, which are type 2 cytokines …

Tumor necrosis factor α (TNF-α) is a major pro-inflammatory cytokine, important in many
diseases, that sensitizes nociceptors through its action on a variety of ion channels …

Peripheral neuropathic pain (PNP), neuropathic pain that arises from a damage or disease
affecting the peripheral nervous system, is associated with an extremely large disease …

Peripheral sensory neurons are a critical part of the nervous system that transmit a multitude
of sensory stimuli to the central nervous system. During larval and juvenile stages in …

Dorsal root ganglia (DRG), trigeminal ganglia (TG), other sensory ganglia, and autonomic
ganglia may be injured by some test article classes, including anti-neoplastic …