[HTML][HTML] Is CAA a perivascular brain clearance disease? A discussion of the evidence to date and outlook for future studies

SJ van Veluw, H Benveniste, ENTP Bakker… - Cellular and Molecular …, 2024 - Springer
The brain's network of perivascular channels for clearance of excess fluids and waste plays
a critical role in the pathogenesis of several neurodegenerative diseases including cerebral …

[HTML][HTML] Hydraulic resistance of three-dimensional pial perivascular spaces in the brain

KAS Boster, J Sun, JK Shang, DH Kelley… - Fluids and Barriers of …, 2024 - Springer
Abstract Background Perivascular spaces (PVSs) carry cerebrospinal fluid (CSF) around the
brain, facilitating healthy waste clearance. Measuring those flows in vivo is difficult, and often …

The directional flow generated by peristalsis in perivascular networks—Theoretical and numerical reduced-order descriptions

IG Gjerde, ME Rognes, AL Sanchez - Journal of Applied Physics, 2023 - pubs.aip.org
Directional fluid flow in perivascular spaces surrounding cerebral arteries is hypothesized to
play a key role in brain solute transport and clearance. While various drivers for a pulsatile …

Parenchymal CSF fraction is a measure of brain glymphatic clearance and positively associated with amyloid beta deposition on PET

L Zhou, TD Nguyen, GC Chiang, XH Wang… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Mapping of microscopic changes in the perivascular space (PVS) of the
cerebral cortex, beyond magnetic resonance‐visible PVS in white matter, may enhance our …

How Irregular Geometry and Complex Feed Waveform Affect Pulsating Arterial Mass Transfer

W Strasser - Journal of Biomechanical Engineering, 2024 - asmedigitalcollection.asme.org
Alzheimer's disease is a progressive degenerative condition that has various levels of effect
on one's memory. It is thought to be caused by a buildup of protein in small fluid-filled …