Descending control of pain

MJ Millan - Progress in neurobiology, 2002 - Elsevier
Upon receipt in the dorsal horn (DH) of the spinal cord, nociceptive (pain-signalling)
information from the viscera, skin and other organs is subject to extensive processing by a …

Spinal circuits for touch, pain, and itch

SC Koch, D Acton, M Goulding - Annual review of physiology, 2018 - annualreviews.org
The exteroceptive somatosensory system is important for reflexive and adaptive behaviors
and for the dynamic control of movement in response to external stimuli. This review outlines …

Immune and inflammatory mechanisms in neuropathic pain

G Moalem, DJ Tracey - Brain research reviews, 2006 - Elsevier
Tissue damage, inflammation or injury of the nervous system may result in chronic
neuropathic pain characterised by increased sensitivity to painful stimuli (hyperalgesia), the …

Dysfunctional endogenous analgesia during exercise in patients with chronic pain: to exercise or not to exercise?

J Nijs, E Kosek, J Van Oosterwijck… - Pain physician, 2012 - repository.uantwerpen.be
Background: Exercise is an effective treatment for various chronic pain disorders, including
fibromyalgia, chronic neck pain, osteoarthritis, rheumatoid arthritis, and chronic low back …

Central sensitization: a biopsychosocial explanation for chronic widespread pain in patients with fibromyalgia and chronic fatigue syndrome

M Meeus, J Nijs - Clinical rheumatology, 2007 - Springer
In addition to the debilitating fatigue, the majority of patients with chronic fatigue syndrome
(CFS) experience chronic widespread pain. These pain complaints show the greatest …

Targeting nitric oxide as a key modulator of sepsis, arthritis and pain

F Spiller, RO Formiga, JF da Silva Coimbra… - Nitric Oxide, 2019 - Elsevier
Nitric oxide (NO) is produced by enzymatic activity of neuronal (nNOS), endothelial (eNOS),
and inducible nitric oxide synthase (iNOS) and modulates a broad spectrum of physiological …

Migraine as an inflammatory disorder

C Waeber, MA Moskowitz - Neurology, 2005 - AAN Enterprises
Migraine as an inflammatory disorder | Neurology Skip to main content Skip to main content
AAN.com AAN Publications Author Center About the Journals Press Releases Go to homepage …

The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache

J Olesen - Pharmacology & therapeutics, 2008 - Elsevier
The most important primary headaches (ie independent disorders that are not caused by
another disease) are migraine, tension-type headache and cluster headache. All primary …

Reduced pressure pain thresholds in response to exercise in chronic fatigue syndrome but not in chronic low back pain: an experimental study.

M Meeus, N Roussel, S Truijen… - Journal of …, 2010 - medicaljournalssweden.se
OBJECTIVE: The aims of this study were to examine:(i) baseline pressure pain thresholds in
patients with chronic fatigue syndrome and those with chronic low back pain compared with …

Poststernotomy pain: a clinical review

M Mazzeffi, Y Khelemsky - Journal of cardiothoracic and vascular …, 2011 - jcvaonline.com
POORLY CONTROLLED PAIN is associated with sympa-thetic nervous system activation
and an increased hormonal stress response. This response may contribute to multiple …