The cancer stem cell (CSC) hypothesis, despite the limitations of the currently available
models and assays, has ushered in a new era of excitement in cancer research. The …

Gastric cancer is a significant global health problem. It is the fifth most common cancer and
third leading cause of cancer-related death worldwide (Torre et al. in CA Cancer J Clin 65 …

Statins purportedly exert anti-tumoral effects on breast cancer. However, the biologic
mechanisms for these actions are not fully elucidated. The aims of this study were 1) to …

Abstract Purpose Systemic Inflammation Response Index (SIRI), based on peripheral
neutrophil, monocyte, and lymphocyte counts, was recently developed and used as a …

Purpose: EphA2, a member of the Eph receptor tyrosine kinases family, is an important
regulator of tumor initiation, neovascularization, and metastasis in a wide range of epithelial …

Head and neck squamous cell carcinoma (HNSCC) is one of the world's top ten most
common cancers. Current survival rates are poor with only 50% of patients expected to …

The existence of gastric cancer stem cells (CSCs) has not been definitively proven and
specific cell surface markers for identifying gastric CSCs have largely not been identified …

In this study we tested the prevalence, histoanatomical distribution and tumour biological
significance of the Wnt target protein and cancer stem cell marker LGR5 in tumours of the …

Pancreatic cancer, mostly pancreatic ductal adenocarcinomas (PDAC), is one of the most
lethal cancers, with a dismal median survival around 8 months. PDAC is notoriously …

Background: Granulocyte colony-stimulating factor (G-CSF) is a pro-inflammatory cytokine
that stimulates myeloid stem cell maturation, proliferation, and migration into circulation …