Genetic variants causing G6PD deficiency: Clinical and biochemical data support new WHO classification
C Nannelli, A Bosman, J Cunningham… - British Journal of …, 2023 - Wiley Online Library
Summary Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency in erythrocytes causes
acute haemolytic anaemia upon exposure to fava beans, drugs, or infection; and it …
acute haemolytic anaemia upon exposure to fava beans, drugs, or infection; and it …
A review of the current status of G6PD deficiency testing to guide radical cure treatment for vivax malaria
Plasmodium vivax malaria continues to cause a significant burden of disease in the Asia-
Pacific, the Horn of Africa, and the Americas. In addition to schizontocidal treatment, the 8 …
Pacific, the Horn of Africa, and the Americas. In addition to schizontocidal treatment, the 8 …
Operational feasibility of Plasmodium vivax radical cure with tafenoquine or primaquine following point-of-care, quantitative glucose-6-phosphate dehydrogenase …
M Brito, R Rufatto, F Murta, V Sampaio… - The Lancet Global …, 2024 - thelancet.com
Background To achieve malaria elimination, Brazil must implement Plasmodium vivax
radical cure. We aimed to investigate the operational feasibility of point-of-care, quantitative …
radical cure. We aimed to investigate the operational feasibility of point-of-care, quantitative …
Field assessment of the operating procedures of a semi-quantitative G6PD Biosensor to improve repeatability of routine testing
In remote communities, diagnosis of G6PD deficiency is challenging. We assessed the
impact of modified test procedures and delayed testing for the point-of-care diagnostic …
impact of modified test procedures and delayed testing for the point-of-care diagnostic …
Potentially pathogenic and pathogenic G6PD variants
In their interesting and comprehensive paper in the February 2, 2023 issue of this journal,
Geck et al. 1 have illustrated several aspects of genetic variation at the X-linked G6PD locus …
Geck et al. 1 have illustrated several aspects of genetic variation at the X-linked G6PD locus …
Field evaluation of a novel semi-quantitative point-of-care diagnostic for G6PD deficiency in Indonesia
Background The WHO recommends routine testing of G6PD activity to guide radical cure in
patients with Plasmodium vivax malaria. Females may have intermediate G6PD enzyme …
patients with Plasmodium vivax malaria. Females may have intermediate G6PD enzyme …
Simultaneous detection of G6PD mutations using SNPscan in a multiethnic minority area of Southwestern China
H Wei, C Wang, W Huang, L He, Y Liu, H Huang… - Frontiers in …, 2023 - frontiersin.org
Objectives: Baise, a multiethnic inhabited area of southwestern China, is a historical malaria-
endemic area with a high prevalence of G6PD deficiency. However, few studies of G6PD …
endemic area with a high prevalence of G6PD deficiency. However, few studies of G6PD …
Substitution of arginine 219 by glycine compromises stability, dimerization, and catalytic activity in a G6PD mutant
O Zgheib, K Chamchoy, T Nouspikel, JL Blouin… - Communications …, 2023 - nature.com
Abstract Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most
common enzymopathies in humans, present in approximately half a billion people …
common enzymopathies in humans, present in approximately half a billion people …
Molecular epidemiological investigation of G6PD deficiency in Yangjiang region, western Guangdong province
HF Liang, YB Cao, F Lin, YK Yang, YW Liao… - Frontiers in …, 2024 - frontiersin.org
Objectives: The prevalence of G6PD deficiency has not been reported in Yangjiang, a
western city in Guangdong province. This study aims to investigate the molecular …
western city in Guangdong province. This study aims to investigate the molecular …
Plasmodium vivax Malaria and G6PD Testing
B Ley, L Luzzatto - Pathogens, 2023 - mdpi.com
Early malaria investigators were certainly correct in classifying the species falciparum and
the species vivax as belonging to the same genus, Plasmodium. Both are intraerythrocytic in …
the species vivax as belonging to the same genus, Plasmodium. Both are intraerythrocytic in …