Conserved signaling modules regulate filamentous growth in fungi: a model for eukaryotic cell differentiation
Eukaryotic organisms are composed of different cell types with defined shapes and
functions. Specific cell types are produced by the process of cell differentiation, which is …
functions. Specific cell types are produced by the process of cell differentiation, which is …
Turnover and bypass of p21-activated kinase during Cdc42-dependent MAPK signaling in yeast
B González, M Mirzaei, S Basu, AN Pujari… - Journal of Biological …, 2023 - ASBMB
Mitogen-activated protein kinase (MAPK) pathways regulate multiple cellular behaviors,
including the response to stress and cell differentiation, and are highly conserved across …
including the response to stress and cell differentiation, and are highly conserved across …
Modulators of MAPK pathway activity during filamentous growth in Saccharomyces cerevisiae
AN Pujari, PJ Cullen - G3: Genes, Genomes, Genetics, 2024 - academic.oup.com
Mitogen-activated protein kinase (MAPK) pathways control the response to intrinsic and
extrinsic stimuli. In the budding yeast Saccharomyces cerevisiae, cells undergo filamentous …
extrinsic stimuli. In the budding yeast Saccharomyces cerevisiae, cells undergo filamentous …
Regulation of Cdc42 protein turnover modulates the filamentous growth MAPK pathway
B González, PJ Cullen - Journal of Cell Biology, 2022 - rupress.org
Rho GTPases are central regulators of cell polarity and signaling. How Rho GTPases are
directed to function in certain settings remains unclear. Here, we show the protein levels of …
directed to function in certain settings remains unclear. Here, we show the protein levels of …
Hsp90 mediates the crosstalk between galactose metabolism and cell morphology pathways in yeast
RK Gopinath, JY Leu - Current genetics, 2017 - Springer
Galactose metabolism in the yeast Saccharomyces cerevisiae is carried out by a specialized
GAL pathway consisting of structural and regulatory proteins. It is known that cells with …
GAL pathway consisting of structural and regulatory proteins. It is known that cells with …
Functions for Cdc42p BEM adaptors in regulating a differentiation-type MAP kinase pathway
S Basu, B González, B Li, G Kimble… - Molecular biology of …, 2020 - Am Soc Cell Biol
Ras homology (Rho) GTPases regulate cell polarity and signal transduction pathways to
control morphogenetic responses in different settings. In yeast, the Rho GTPase Cdc42p …
control morphogenetic responses in different settings. In yeast, the Rho GTPase Cdc42p …
Aggregate filamentous growth responses in yeast
J Chow, HM Dionne, A Prabhakar, A Mehrotra… - Msphere, 2019 - Am Soc Microbiol
Many fungal species, including pathogens, undergo a morphogenetic response called
filamentous growth, where cells differentiate into a specialized cell type to promote nutrient …
filamentous growth, where cells differentiate into a specialized cell type to promote nutrient …
Signalling mucin Msb2 Regulates adaptation to thermal stress in Candida albicans
D Saraswat, R Kumar, T Pande… - Molecular …, 2016 - Wiley Online Library
Temperature is a potent inducer of fungal dimorphism. Multiple signalling pathways control
the response to growth at high temperature, but the sensors that regulate these pathways …
the response to growth at high temperature, but the sensors that regulate these pathways …
Scaffold protein Ahk1, which associates with Hkr1, Sho1, Ste11, and Pbs2, inhibits cross talk signaling from the Hkr1 osmosensor to the Kss1 mitogen-activated …
A Nishimura, K Yamamoto, M Oyama… - … and cellular biology, 2016 - Am Soc Microbiol
In the budding yeast Saccharomyces cerevisiae, osmostress activates the Hog1 mitogen-
activated protein kinase (MAPK), which regulates diverse osmoadaptive responses. Hkr1 is …
activated protein kinase (MAPK), which regulates diverse osmoadaptive responses. Hkr1 is …
Growth hormone releasing hormone in the unfolded protein response context
N Barabutis - Endocrine, 2020 - Springer
Abstract The effects of Growth Hormone Releasing Hormone in human pathophysiology are
not limited to those mediated by the Growth Hormone Releasing Hormone–Growth …
not limited to those mediated by the Growth Hormone Releasing Hormone–Growth …