Toward Optogenetic Hearing Restoration
The cochlear implant (CI) is considered the most successful neuroprosthesis as it enables
speech comprehension in the majority of the million otherwise deaf patients. In hearing by …
speech comprehension in the majority of the million otherwise deaf patients. In hearing by …
[HTML][HTML] Spread of activation and interaction between channels with multi-channel optogenetic stimulation in the mouse cochlea
For individuals with severe to profound hearing loss resulting from irreversibly damaged hair
cells, cochlear implants can be used to restore hearing by delivering electrical stimulation …
cells, cochlear implants can be used to restore hearing by delivering electrical stimulation …
En route to sound coding strategy for optical cochlear implants
L Khurana, T Harczos, T Moser, L Jablonski - Iscience, 2023 - cell.com
In 2019, disabling hearing loss affected 430 million people worldwide and will reach over
700 million by 2050. Severe-to-complete sensorineural hearing loss is often treated by …
700 million by 2050. Severe-to-complete sensorineural hearing loss is often treated by …
Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users
V Hunniford, R Kühler, B Wolf, D Keppeler… - Frontiers in …, 2023 - frontiersin.org
Background The electrical cochlear implant (eCI) partially restores hearing in individuals
affected by profound hearing impairment (HI) or deafness. However, the limited resolution of …
affected by profound hearing impairment (HI) or deafness. However, the limited resolution of …
[HTML][HTML] Graded optogenetic activation of the auditory pathway for hearing restoration
Optogenetic control of neural activity enables innovative approaches to improve functional
restoration of diseased sensory and motor systems. For clinical translation to succeed …
restoration of diseased sensory and motor systems. For clinical translation to succeed …
[HTML][HTML] Devising a framework of optogenetic coding in the auditory pathway: Insights from auditory midbrain recordings
M Michael, BJ Wolf, A Klinge-Strahl, M Jeschke… - Brain Stimulation, 2023 - Elsevier
Cochlear implants (CIs) restore activity in the deafened auditory system via electrical
stimulation of the auditory nerve. As the spread of electric current in biological tissues is …
stimulation of the auditory nerve. As the spread of electric current in biological tissues is …
Channelrhodopsin fluorescent tag replacement for clinical translation of optogenetic hearing restoration
Sensory restoration by optogenetic neurostimulation provides a promising future alternative
to current electrical stimulation approaches. So far, channelrhodopsins (ChRs) typically …
to current electrical stimulation approaches. So far, channelrhodopsins (ChRs) typically …
Fraxicon for optical applications with aperture∼ 1 mm: characterisation study
Emerging applications of optical technologies are driving the development of miniaturised
light sources, which in turn require the fabrication of matching micro-optical elements with …
light sources, which in turn require the fabrication of matching micro-optical elements with …
[HTML][HTML] Implantes cocleares ópticos: una herramienta promisoria de tratamiento para la hipoacusia
V Sepúlveda, J Osorio - Revista de otorrinolaringología y cirugía de …, 2023 - SciELO Chile
La hipoacusia afecta a más de 1.500 millones de personas mundialmente. Los principales
medios de rehabilitación usados son los audífonos e implantes cocleares (IC). El IC …
medios de rehabilitación usados son los audífonos e implantes cocleares (IC). El IC …
Fraxicon for Optical Applications with Aperture∼ 1 mm
Emerging applications of optical technologies are driving the development of miniaturised
light sources, which in turn require the fabrication of matching micro-optical elements with …
light sources, which in turn require the fabrication of matching micro-optical elements with …