Using photo-initiated polymerization reactions to detect molecular recognition
K Kaastrup, HD Sikes - Chemical Society Reviews, 2016 - pubs.rsc.org
Widely used medical diagnostic devices and assays that sense the presence of a particular
molecule in a bodily fluid often rely on either a nanoparticle label or an enzymatic reaction to …
molecule in a bodily fluid often rely on either a nanoparticle label or an enzymatic reaction to …
Advances in microfluidic-based DNA methylation analysis
J Li, T Li, X Duan - Nanotechnology and Precision Engineering, 2024 - pubs.aip.org
ABSTRACT DNA methylation has been extensively investigated in recent years, not least
because of its known relationship with various diseases. Progress in analytical methods can …
because of its known relationship with various diseases. Progress in analytical methods can …
Substituent Effects of Fluorescein on Photoredox Initiating Performance under Visible Light
We demonstrated the effects of substituents in fluorescein on the photoredox catalytic
performance under visible light. For the systematic investigation, the phenyl ring of …
performance under visible light. For the systematic investigation, the phenyl ring of …
Detection of CpG methylation level using methyl-CpG-binding domain-fused fluorescent protein
Methylation of cytosine to 5-methylcytosine on CpG dinucleotides is the most frequently
studied epigenetic modification involved in the regulation of gene expression. In normal …
studied epigenetic modification involved in the regulation of gene expression. In normal …
Photoinduced radical polymerization by methyl fluoresceins under visible light and the application to signal amplification of hydrogen peroxide
We investigate visible‒light‒induced radical polymerization initiated by methyl fluorescein
and its derivatives (eg, methyl ether of fluorescein, methyl ether ester of fluorescein, and …
and its derivatives (eg, methyl ether of fluorescein, methyl ether ester of fluorescein, and …
Microfluidic platforms for DNA methylation analysis
In the field of genetics, epigenetics is the study of changes in gene expression without any
change in DNA sequences. Chemical base modification in DNA by DNA methyltransferase …
change in DNA sequences. Chemical base modification in DNA by DNA methyltransferase …
Microfluidic epigenomic mapping technologies for precision medicine
Epigenomic mapping of tissue samples generates critical insights into genome-wide
regulations of gene activities and expressions during normal development and disease …
regulations of gene activities and expressions during normal development and disease …
Investigation of dendrimers functionalized with eosin as macrophotoinitiators for polymerization-based signal amplification reactions
K Kaastrup, HD Sikes - RSC Advances, 2015 - pubs.rsc.org
Polymerization-based signal amplification, a technique developed for use in rapid
diagnostic tests, hinges on the ability to localize initiators as a function of interfacial binding …
diagnostic tests, hinges on the ability to localize initiators as a function of interfacial binding …
Label-free detection of missense mutations and methylation differences in the p53 gene using optically diffracting hydrogels
We have developed a novel approach for DNA detection as well as genetic screening of
mutations by uniquely combining DNA-responsive and optically diffracting materials. This …
mutations by uniquely combining DNA-responsive and optically diffracting materials. This …
The heavy-atom effect on xanthene dyes for photopolymerization by visible light
J Yoon, YJ Jung, JB Yoon, K Damodar, H Kim… - Polymer …, 2019 - pubs.rsc.org
We investigated the influence of heavy halogen atoms (Br and I) on xanthene dyes for
polymerization based on visible-light photoredox initiation. Since the heavy atoms directly …
polymerization based on visible-light photoredox initiation. Since the heavy atoms directly …