The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine
G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023 - ACS Publications
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …
The L-type amino acid transporter LAT1—An emerging target in cancer
P Häfliger, RP Charles - International journal of molecular sciences, 2019 - mdpi.com
Chronic proliferation is a major hallmark of tumor cells. Rapidly proliferating cancer cells are
highly dependent on nutrients in order to duplicate their cell mass during each cell division …
highly dependent on nutrients in order to duplicate their cell mass during each cell division …
NOREVA: normalization and evaluation of MS-based metabolomics data
Diverse forms of unwanted signal variations in mass spectrometry-based metabolomics data
adversely affect the accuracies of metabolic profiling. A variety of normalization methods …
adversely affect the accuracies of metabolic profiling. A variety of normalization methods …
Metabolomics in cancer biomarker discovery: current trends and future perspectives
EG Armitage, C Barbas - Journal of pharmaceutical and biomedical …, 2014 - Elsevier
Cancer is one of the most devastating human diseases that causes a vast number of
mortalities worldwide each year. Cancer research is one of the largest fields in the life …
mortalities worldwide each year. Cancer research is one of the largest fields in the life …
The serum amino acid profile in COVID-19
The pandemic of the coronavirus disease (COVID-19) caused by SARS-CoV-2 affects
millions of people worldwide. There are still many unknown aspects to this infection which …
millions of people worldwide. There are still many unknown aspects to this infection which …
Integrated analysis of colorectal cancer reveals cross-cohort gut microbial signatures and associated serum metabolites
R Gao, C Wu, Y Zhu, C Kong, Y Zhu, Y Gao, X Zhang… - Gastroenterology, 2022 - Elsevier
Background & Aims Studies have reported abnormal gut microbiota or circulating
metabolome associated with colorectal cancer (CRC), but it remains a challenge to capture …
metabolome associated with colorectal cancer (CRC), but it remains a challenge to capture …
Colorectal cancer detection using targeted serum metabolic profiling
Colorectal cancer (CRC) is one of the most prevalent and deadly cancers in the world.
Despite an expanding knowledge of its molecular pathogenesis during the past two …
Despite an expanding knowledge of its molecular pathogenesis during the past two …
Pharmacometabonomics: data processing and statistical analysis
J Fu, Y Zhang, J Liu, X Lian, J Tang… - Briefings in …, 2021 - academic.oup.com
Individual variations in drug efficacy, side effects and adverse drug reactions are still
challenging that cannot be ignored in drug research and development. The aim of …
challenging that cannot be ignored in drug research and development. The aim of …
Performance evaluation and online realization of data-driven normalization methods used in LC/MS based untargeted metabolomics analysis
In untargeted metabolomics analysis, several factors (eg, unwanted experimental &
biological variations and technical errors) may hamper the identification of differential …
biological variations and technical errors) may hamper the identification of differential …
Metabolomics in diagnosis and biomarker discovery of colorectal cancer
A Zhang, H Sun, G Yan, P Wang, Y Han, X Wang - Cancer letters, 2014 - Elsevier
Colorectal cancer (CRC), a major public health concern, is the second leading cause of
cancer death in developed countries. There is a need for better preventive strategies to …
cancer death in developed countries. There is a need for better preventive strategies to …