Developing Aspergillus niger as a cell factory for food enzyme production

C Li, J Zhou, G Du, J Chen, S Takahashi, S Liu - Biotechnology Advances, 2020 - Elsevier
Aspergillus niger has become one of the most important hosts for food enzyme production
due to its unique food safety characteristics and excellent protein secretion systems. A series …

Nature and regulation of protein folding on the ribosome

CA Waudby, CM Dobson, J Christodoulou - Trends in biochemical …, 2019 - cell.com
Co-translational protein folding is an essential process by which cells ensure the safe and
efficient production and assembly of new proteins in their functional native states following …

Current structure predictors are not learning the physics of protein folding

C Outeiral, DA Nissley, CM Deane - Bioinformatics, 2022 - academic.oup.com
Motivation. Predicting the native state of a protein has long been considered a gateway
problem for understanding protein folding. Recent advances in structural modeling driven by …

Evolution of Escherichia coli Expression System in Producing Antibody Recombinant Fragments

A Sandomenico, JP Sivaccumar, M Ruvo - International Journal of …, 2020 - mdpi.com
Antibodies and antibody-derived molecules are continuously developed as both therapeutic
agents and key reagents for advanced diagnostic investigations. Their application in these …

Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection

F Chen, P Wu, S Deng, H Zhang, Y Hou, Z Hu… - Nature ecology & …, 2020 - nature.com
Eighteen of the 20 amino acids are each encoded by more than one synonymous codon.
Due to differential transfer RNA supply within the cell, synonymous codons are not used with …

Highly active rubiscos discovered by systematic interrogation of natural sequence diversity

D Davidi, M Shamshoum, Z Guo, YM Bar‐On… - The EMBO …, 2020 - embopress.org
CO 2 is converted into biomass almost solely by the enzyme rubisco. The poor carboxylation
properties of plant rubiscos have led to efforts that made it the most kinetically characterized …

Folding of heterologous proteins in bacterial cell factories: Cellular mechanisms and engineering strategies

Y Rong, SI Jensen, K Lindorff-Larsen… - Biotechnology Advances, 2023 - Elsevier
The expression of correctly folded and functional heterologous proteins is important in many
biotechnological production processes, whether it is enzymes, biopharmaceuticals or …

Genetic and metabolic engineering challenges of C1-gas fermenting acetogenic chassis organisms

B Bourgade, NP Minton, MA Islam - FEMS Microbiology …, 2021 - academic.oup.com
Unabated mining and utilisation of petroleum and petroleum resources and their conversion
to essential fuels and chemicals have drastic environmental consequences, contributing to …

Applications of protein engineering and directed evolution in plant research

MKM Engqvist, KS Rabe - Plant physiology, 2019 - academic.oup.com
Applications of Protein Engineering and Directed Evolution in Plant Research | Plant
Physiology | Oxford Academic Skip to Main Content Advertisement Oxford Academic …

Heterologous production of cellulose-and starch-degrading hydrolases to expand Saccharomyces cerevisiae substrate utilization: lessons learnt

R den Haan, SH Rose, RA Cripwell, KM Trollope… - Biotechnology …, 2021 - Elsevier
Selected strains of Saccharomyces cerevisiae are used for commercial bioethanol
production from cellulose and starch, but the high cost of exogenous enzymes for substrate …