An important role for bioenergetic dysfunction is increasingly emerging to potentially explain
the paradox of clinical and biochemical organ failure in sepsis yet minimal cell death …

Organisms that tolerate wide variations in oxygen availability, especially to hypoxia, usually
face harsh environmental conditions during their lives. Such conditions include, for example …

Extended bouts of fasting are ingrained in the ecology of many organisms, characterizing
aspects of reproduction, development, hibernation, estivation, migration, and infrequent …

Fasting is a component of many species' life history due to environmental factors or
behavioral patterns that limit access to food. Despite metabolic and physiological challenges …

Antibiotic resistance is a global health crisis increasing in prevalence every day. To combat
this crisis, alternative antimicrobial therapeutics are urgently needed. Antimicrobial peptides …

It is well known that many anoxia/hypoxia tolerant species when exposed to anoxia/hypoxia
respond by increasing the activity/expression of antioxidant enzymes and/or glutathione …

Highlights•We describe tuning of temperature receptors in cold-blooded and warm-blooded
animals.•Somatosensory system interacts with the environment to support survival.•Non …

Adult stem cells (ASCs) in vertebrates and model invertebrates (eg Drosophila
melanogaster) are typically long‐lived, lineage‐restricted, clonogenic and quiescent cells …

Bone mass and skeletal muscle mass are controlled by factors such as genetics, diet and
nutrition, growth factors and mechanical stimuli. Whereas increased mechanical loading of …

Background Cope's gray treefrog, Dryophytes chrysoscelis, withstands the physiological
challenges of corporeal freezing, partly by accumulating cryoprotective compounds of …