The extracellular matrix in skin inflammation and infection
K Pfisterer, LE Shaw, D Symmank… - Frontiers in cell and …, 2021 - frontiersin.org
The extracellular matrix (ECM) is an integral component of all organs and plays a pivotal
role in tissue homeostasis and repair. While the ECM was long thought to mostly have …
role in tissue homeostasis and repair. While the ECM was long thought to mostly have …
Mechanomaterials: a rational deployment of forces and geometries in programming functional materials
The knowledge of mechanics of materials has been extensively implemented in developing
functional materials, giving rise to recent advances in soft actuators, flexible electronics …
functional materials, giving rise to recent advances in soft actuators, flexible electronics …
[HTML][HTML] Three-dimensional (3D) scaffolds as powerful weapons for tumor immunotherapy
S Han, J Wu - Bioactive Materials, 2022 - Elsevier
Though increasing understanding and remarkable clinical successes have been made,
enormous challenges remain to be solved in the field of cancer immunotherapy. In this …
enormous challenges remain to be solved in the field of cancer immunotherapy. In this …
Modulating tumor physical microenvironment for fueling CAR-T cell therapy
Z Luo, X Yao, M Li, D Fang, Y Fei, Z Cheng, Y Xu… - Advanced drug delivery …, 2022 - Elsevier
Chimeric antigen receptor (CAR) T cell therapy has achieved unprecedented clinical
success against hematologic malignancies. However, the transition of CAR-T cell therapies …
success against hematologic malignancies. However, the transition of CAR-T cell therapies …
Multiple aspects of matrix stiffness in cancer progression
A Mancini, MT Gentile, F Pentimalli… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
The biophysical and biomechanical properties of the extracellular matrix (ECM) are crucial
in the processes of cell differentiation and proliferation. However, it is unclear to what extent …
in the processes of cell differentiation and proliferation. However, it is unclear to what extent …
[HTML][HTML] Extracellular matrix components and mechanosensing pathways in health and disease
A Berdiaki, M Neagu, P Tzanakakis, I Spyridaki… - Biomolecules, 2024 - mdpi.com
Glycosaminoglycans (GAGs) and proteoglycans (PGs) are essential components of the
extracellular matrix (ECM) with pivotal roles in cellular mechanosensing pathways. GAGs …
extracellular matrix (ECM) with pivotal roles in cellular mechanosensing pathways. GAGs …
Mechanistic insights into the development of severe fetal growth restriction
DL Gumina, EJ Su - Clinical Science, 2023 - portlandpress.com
Fetal growth restriction (FGR), which most commonly results from suboptimal placental
function, substantially increases risks for adverse perinatal and long-term outcomes. The …
function, substantially increases risks for adverse perinatal and long-term outcomes. The …
Genetic variation drives cancer cell adaptation to ECM stiffness
The progression of many solid tumors is accompanied by temporal and spatial changes in
the stiffness of the extracellular matrix (ECM). Cancer cells adapt to soft and stiff ECM …
the stiffness of the extracellular matrix (ECM). Cancer cells adapt to soft and stiff ECM …
Applicability of atomic force microscopy to determine cancer-related changes in cells
M Lekka - … Transactions of the Royal Society A, 2022 - royalsocietypublishing.org
The determination of mechanical properties of living cells as an indicator of cancer
progression has become possible with the development of local measurement techniques …
progression has become possible with the development of local measurement techniques …