Innate lymphoid cell memory
X Wang, H Peng, Z Tian - Cellular & Molecular Immunology, 2019 - nature.com
Innate lymphoid cells (ILCs), including natural killer (NK) cells, ILC1s, ILC2s, ILC3s, and
lymphoid tissue inducer (LTi) cells, comprise the first line of innate immune defense against …
lymphoid tissue inducer (LTi) cells, comprise the first line of innate immune defense against …
Natural killer cells for antiviral therapy
DM Smith, JR Schafer, B Tullius, L Witkam… - Science Translational …, 2023 - science.org
Natural killer (NK) cell–based immunotherapy is being explored for treating infectious
diseases, including viral infections. Here, we discuss evidence of NK cell responses to …
diseases, including viral infections. Here, we discuss evidence of NK cell responses to …
Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression
Human adaptive-like natural killer (NK) cells express low levels of FcεRIγ (FcRγ−/low) and
are reported to accumulate during COVID-19 infection; however, the mechanism underlying …
are reported to accumulate during COVID-19 infection; however, the mechanism underlying …
Natural killer cells regulate acute SIV replication, dissemination, and inflammation, but do not impact independent transmission events
G Woolley, M Mosher, K Kroll, R Jones… - Journal of …, 2023 - Am Soc Microbiol
Natural killer (NK) cells are potent effector cells of the innate immune system possessing
both cytotoxic and immunoregulatory capabilities, which contribute to their crucial role in …
both cytotoxic and immunoregulatory capabilities, which contribute to their crucial role in …
Cytomegalovirus as an immunomodulator across the lifespan
Highlights•Human cytomegalovirus (HCMV) infection and HCMV-seropositivity have an age-
dependent impact on health and disease.•HCMV is associated with adverse health …
dependent impact on health and disease.•HCMV is associated with adverse health …
Vaccine induced mucosal and systemic memory NK/ILCs elicit decreased risk of SIV/SHIV acquisition
SIV and HIV-based envelope V1-deleted (ΔV1) vaccines, delivered systemically by the
DNA/ALVAC/gp120 platform, decrease the risk of mucosal SIV or SHIV acquisition more …
DNA/ALVAC/gp120 platform, decrease the risk of mucosal SIV or SHIV acquisition more …
Natural killer cell responses during SARS-CoV-2 infection and vaccination in people living with HIV-1
Natural killer (NK) cell subsets with adaptive properties are emerging as regulators of
vaccine-induced T and B cell responses and are specialized towards antibody-dependent …
vaccine-induced T and B cell responses and are specialized towards antibody-dependent …
Virus-specific NK cell memory
S Sheppard, JC Sun - Journal of Experimental Medicine, 2021 - rupress.org
NK cells express a limited number of germline-encoded receptors that identify infected or
transformed cells, eliciting cytotoxicity, effector cytokine production, and in some …
transformed cells, eliciting cytotoxicity, effector cytokine production, and in some …
Knowns and unknowns of assaying antibody-dependent cell-mediated cytotoxicity against HIV-1
GK Lewis, ME Ackerman, G Scarlatti, C Moog… - Frontiers in …, 2019 - frontiersin.org
It is now well-accepted that Fc-mediated effector functions, including antibody-dependent
cellular cytotoxicity (ADCC), can contribute to vaccine-elicited protection as well as post …
cellular cytotoxicity (ADCC), can contribute to vaccine-elicited protection as well as post …
NK cells modulate in vivo control of SARS-CoV-2 replication and suppression of lung damage
Natural killer (NK) cells play a critical role in virus control. However, it has remained largely
unclear whether NK cell mobilization in SARS-CoV-2 infections is beneficial or pathologic …
unclear whether NK cell mobilization in SARS-CoV-2 infections is beneficial or pathologic …