Objective: To review pharmacokinetic and pharmacodynamic drug–drug interactions (DDIs)
involving new oral anticoagulants for atrial fibrillation. Data Sources: A literature search was …

In recent years, the growing numbers of patients seeking care for a wide range of psychiatric
illnesses in the primary care setting has resulted in an increase in the number of …

Objective Apixaban is a substrate of cytochrome P450 3A4 (CYP3A4) and P-glycoprotein.
The effects of rifampin, a strong inducer of CYP3A4 and P-glycoprotein, on the …

Ethnopharmacological relevance Traditional healers have used medicinal plants to treat
snakebite envenomation worldwide; however, mostly without scientific validation. There …

Background: A recently FDA approved 3D printed drug is paving a path for new
pharmaceutical manufacturing era. The 3D printing is a novel approach of producing 3D …

The World Health Organization has declared snakebite as a neglected tropical disease.
Antivenom administration is the sole therapy against venomous snakebite; however, several …

Nanotechnology is a multidisciplinary scientific field that deals with the formulation,
preparation, characterization and application of structures, devices and systems at …

La ciencia llamada farmacología pediátrica estudia los fármacos usados en estas
poblaciones etarias, donde se observan diferencias importantes con los adultos en la …

Glycyrrhizin (GZ), the main active component of licorice, is a widely used therapeutic in the
clinic. Depending on the disease, the treatment may involve a long course of high dose GZ …

After administration, drugs go through a complex, dynamic process of absorption,
distribution, metabolism and excretion. The resulting time-dependent concentration, termed …