Natural killer (NK) cells have long been considered to be a homogenous population of
innate lymphocytes with limited phenotypic and functional diversity. However, recent …

Understanding how signals are integrated to control natural killer (NK) cell responsiveness
in the absence of antigen-specific receptors has been a challenge, but recent work has …

The Fc receptor CD16 is present on essentially all CD56dim peripheral blood natural killer
(NK) cells. Upon recognition of antibody-coated cells it delivers a potent signal to NK cells …

Natural killer (NK) cells express an array of germ‐line encoded receptors that are capable of
triggering cytotoxicity. NK cells tend to express many members of a given family of signalling …

Objective Systemic juvenile idiopathic arthritis (JIA) is associated with high levels of
interleukin‐6 (IL‐6) in the serum and synovial fluid, and impairment of natural killer (NK) cell …

Background Cytokines play multiple roles during neuro-inflammatory processes and several
cytokines have been studied in the context of specific diseases. This study provides a …

The upregulation of heme oxygenase-1 (HO-1) is one of the most important mechanisms of
cell adaptation to stress. Indeed, the redox sensitive transcription factor Nrf2 is the pivotal …

Mesenchymal stromal cells (MSCs) support hematopoiesis and exert immunoregulatory
activities. Here, we analyzed the functional outcome of the interactions between MSCs and …

First described 40 years ago, natural killer (NK) cells represent the founding members of the
innate lymphoid cell (ILC) family. They were initially defined by their ability to kill cancer cells …

Natural killer (NK) cell‐mediated cytotoxicity is governed by the formation of a lytic immune
synapse in discrete regulated steps, which give rise to an extensive array of cellular …