Causative links between ER stress and oxidative damage in a yeast model of human N88S seipinopathy

Combining Metabolic Engineering and Lipid Droplet Assembly to Achieve Campesterol Overproduction in Saccharomyces cerevisiae

Z Qin, Y Zhang, S Liu, W Zeng, J Zhou… - Journal of Agricultural …, 2024 - ACS Publications

Campesterol is a kind of important functional food additive. Therefore, stable and efficient
campesterol biosynthesis is significant. Herein, we first knocked out the sterol 22-desaturase …

被引用次数：3 相关文章所有 3 个版本

Overexpression of genes by stress-responsive promoters increases protein secretion in Saccharomyces cerevisiae

C Xiao, S Xue, Y Pan, X Liu, M Huang - World Journal of Microbiology and …, 2023 - Springer

Recombinant proteins produced by cell factories are now widely used in various fields.
Many efforts have been made to improve the secretion capacity of cell factories to meet the …

被引用次数：5 相关文章所有 3 个版本

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Oxidative stress in N88S seipinopathy: novel insights into the mechanisms of neurodegeneration and therapeutic avenues

V Costa, V Teixeira - Neural Regeneration Research, 2023 - journals.lww.com

Lipid droplets (LDs) are ubiquitous cellular organelles that perform functions mostly
dedicated to energy homeostasis and lipid metabolism. As neutral lipid depots …

酵母模型中ER 应激和氧化损伤之间的因果关系

V Costa, V Teixeira - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn

Lipid droplets (LDs) are ubiquitous cellular organelles that perform functions mostly
dedicated to energy homeostasis and lipid metabolism. As neutral lipid depots …

N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis

MO Ribeiro, M Oliveira, V Nogueira, V Costa… - 2024 - researchsquare.com

Background Seipin is a protein encoded by the BSCL2 gene in humans and SEI1 gene in
yeast, forming an Endoplasmic Reticulum (ER)-bound homo-oligomer. This oligomer is …