Adaptive immune responses to Kaposi's sarcoma-associated herpesvirus

A Nalwoga, D Whitby - Current opinion in immunology, 2022 - Elsevier
Highlights•T cell responses to KSHV are diverse and weak compared to other
herpesviruses.•CD8+ T cells in KS tumours are localised to regions that are KSHV LANA …

Evaluation of human herpesvirus‐8 viremia and antibody positivity in patients with HIV infection with human herpesvirus‐8‐related diseases

D Watanabe, S Iida, K Hirota, T Ueji… - Journal of Medical …, 2023 - Wiley Online Library
Abstract Human herpesvirus‐8 (HHV‐8) viremia is associated with refractory conditions in
patients infected with HIV‐1. Therefore, we evaluated the factors related to plasma HHV‐8 …

Comparative polar and lipid plasma metabolomics differentiate KSHV infection and disease states

SR Privatt, CP Braga, A Johnson, SJ Lidenge… - Cancer & …, 2023 - Springer
Background Kaposi sarcoma (KS) is a neoplastic disease etiologically associated with
infection by the Kaposi sarcoma-associated herpesvirus (KSHV). KS manifests primarily as …

Antibody epitope profiling of the KSHV LANA protein using VirScan

SJ Bennett, D Yalcin, SR Privatt, O Ngalamika… - PLoS …, 2022 - journals.plos.org
The humoral antibody response against Kaposi sarcoma-associated herpesvirus (KSHV) in
infected individuals has been characterized demonstrating the latency-associated nuclear …

Antibody profiling and predictive modeling discriminate between Kaposi sarcoma and asymptomatic KSHV infection

SJ Bennett, D Yalcin, SR Privatt, O Ngalamika… - PLoS …, 2024 - journals.plos.org
Protein-level immunodominance patterns against Kaposi sarcoma-associated herpesvirus
(KSHV), the aetiologic agent of Kaposi sarcoma (KS), have been revealed from serological …

Kaposi's sarcoma, biologics and small molecules: Navigating the complex interplay between host immunity and viral biology. A case series with focused review of the …

L Brambilla, CA Maronese, E Zelin… - Dermatologic …, 2022 - Wiley Online Library
The consequences of cytokine‐specific immune modulation in the development and course
of Kaposi's sarcoma (KS) are poorly understood. A retrospective chart review of patients …

Association between KSHV-Specific Humoral and T Cell Responses with Recurrence of HIV-Associated Kaposi Sarcoma

MC Mukasine, G Mulundu, M Kawimbe… - Tropical Medicine and …, 2024 - mdpi.com
Kaposi sarcoma (KS) is an AIDS-defining angio-proliferative malignancy, with the Kaposi
sarcoma-associated herpes virus (KSHV) as its etiologic agent. Upon treatment with …

Cells of the Innate and Adaptive Immune Systems in Kaposi's Sarcoma

O Ngalamika, S Munsaka - Journal of immunology research, 2020 - Wiley Online Library
Kaposi's sarcoma (KS) is an angioproliferative malignancy whose associated etiologic agent
is the Kaposi's sarcoma‐associated herpesvirus (KSHV). KS is the most prevalent …