N-succinyl-chitosan (Suc-Chi) has favourable properties as a drug carrier such as
biocompatibility, low toxicity and long-term retention in the body. It was long retained in the …

Lectins are glycoproteins or oligomeric proteins with one or more sugar-binding site (s) per
subunit. These molecules are of nonimmune origin and bind reversibly with specific sugars …

The hepatic receptor for asialoglycoproteins was initially demonstrated in the early 1970s by
the seminal studies of Ashwell, Morel], and their colleagues during investigations of the …

Nucleotides have shown interesting biological activities in a wide variety of antiviral,
antiproliferative, immunomodulatory and other biological assays, and they present …

Lactosaminated N-succinyl-chitosan (Lac-Suc) was prepared by reductive amination of N-
succinyl-chitosan (Suc) and lactose using sodium cyanoborohydride. Six-day reaction using …

The expression of the asialoglycoprotein receptor on the cells of the large majority of the
well differentiated hepatocellular carcinomas can be exploited to improve the chemotherapy …

Polymers have found applications in virtually every discipline of medicine, ranging from
simple extracorporeal devices to intricately designed implants. Since each medical …

Background Worldwide, consistent survival benefit for chemotherapy in hepatocellular
carcinoma (HCC) is a golden goal for concerned researchers. Nexavar®(sorafenib) is the …

Complex carbohydrates and sugar receptors at the surface of eukaryotic cells are involved
in recognition phenomena. Membrane lectins have been characterized, using biochemical …

Akin to a cellular “fingerprint,” the glycocalyx is a glycan‐enriched cellular coating that plays
a crucial role in mediating cell‐to‐cell interactions. To gain a better understanding of the …