Objective: To review the present status of bioartificial liver (BAL) devices and their obtained
clinical results. Background: Acute liver failure (ALF) is a disease with a high mortality …

Liver failure, notwithstanding advances in medical management, remains a cause of
considerable morbidity and mortality in the developed world. Although bioartificial liver …

Recently a bio-artificial liver (BAL) system has been developed at the Academic Medical
Center (AMC) of Amsterdam to bridge patients with acute liver failure (ALF) to orthotopic liver …

Recent progress in the use of decellularized organ scaffolds as regenerative matrices for
tissue engineering holds great promise in addressing the issue of donor organ shortage …

A major roadblock to the application of bioartificial livers is the need for a human liver cell
line that displays a high and broad level of hepatic functionality. The human bipotent liver …

Fulminant hepatic failure is a clinical syndrome defined by acute liver injury leading to
hepatic encephalopathy within 8 weeks of the onset of jaundice. Even though the acute …

The aim of this study was to assess the classification accuracy of an e-Nose in detecting
acute liver failure (ALF) in rats. Exhaled breath from 14 rats was repeatedly sampled by e …

The aim of this work was to investigate the protective role of baker's yeast Saccharomyces
cerevisiae against the hepatotoxic effect of the drug flutamide that is widely used for …

Background. The anhepatic pig model was used to evaluate a bioartificial liver developed in
our institution (AMC-BAL). The bioartificial liver is based on oxygenated plasma perfusion of …

Introduction: Bioartificial livers (BALs) are urgently needed to bridge severe liver failure
patients to liver transplantation or liver regeneration. When based on primary hepatocytes …