Human malignancies arise predominantly in tissues of epithelial origin, where the stepwise
transformation from healthy epithelium to premalignant dysplasia to invasive neoplasia …

Cancer is the second most common cause of mortality and morbidity in kidney transplant
recipients after cardiovascular disease. Kidney transplant recipients have at least a twofold …

Context Solid organ transplant recipients have elevated cancer risk due to
immunosuppression and oncogenic viral infections. Because most prior research has …

Background Transplant recipients in whom cutaneous squamous-cell carcinomas develop
are at high risk for multiple subsequent skin cancers. Whether sirolimus is useful in the …

The long-term management of maintenance immunosuppression in kidney transplant
recipients remains complex. The vast majority of patients are treated with the calcineurin …

Objective: To review the literature on current management of hepatocellular carcinoma
(HCC). Background: Hepatocellular carcinoma represents one of the most common …

Malignancy has become one of the three major causes of death after transplantation in the
past decade and is thus increasingly important in all organ transplant programs. Death from …

Kaposi's sarcoma (KS) is a multifocal neoplasm of lymphatic endothelium-derived cells
infected with human herpesvirus 8. Four clinical subtypes are distinguished: the classic, the …

As newer immunosuppressive regimens have steadily reduced the incidence of acute
rejection and have extended the life expectancy of allograft recipients, posttransplant …

Renal transplant recipients have increased mortality rates when compared with the general
population. The new immunosuppressive drugs have improved short-term patient survival …