Corneal stromal repair and regeneration

RR Mohan, D Kempuraj, S D'Souza, A Ghosh - Progress in retinal and eye …, 2022 - Elsevier
The cornea is a specialized, transparent, avascular, immune-privileged, and heavily
innervated tissue that affords 2/3rd of refraction to the eye. Ocular injuries, infections, and …

The pathomechanism, antioxidant biomarkers, and treatment of oxidative stress-related eye diseases

YJ Hsueh, YN Chen, YT Tsao, CM Cheng… - International Journal of …, 2022 - mdpi.com
Oxidative stress is an important pathomechanism found in numerous ocular degenerative
diseases. To provide a better understanding of the mechanism and treatment of …

Corneal stromal wound healing: Major regulators and therapeutic targets

S Kamil, RR Mohan - The ocular surface, 2021 - Elsevier
Corneal stromal wound healing is a complex event that occurs to restore the transparency of
an injured cornea. It involves immediate apoptosis of keratocytes followed by their activation …

Evaluation of protective effects of quercetin against cypermethrin‐induced lung toxicity in rats via oxidative stress, inflammation, apoptosis, autophagy, and …

M Ileriturk, O Kandemir… - Environmental …, 2022 - Wiley Online Library
Cypermethrin (CYP), a type II synthetic pyrethroid, is the most widely used insecticide
worldwide. Inhalation of it may cause side effects. This study is aimed to examine potential …

Morin attenuates acrylamide-induced testicular toxicity in rats by regulating the NF-κB, Bax/Bcl-2 and PI3K/Akt/mTOR signaling pathways

S Kucukler, C Caglayan, E Darendelioğlu… - Life Sciences, 2020 - Elsevier
Aim Acrylamide (AC) is a carcinogenic substance which is formed during the heating of
starchy foods at high temperatures and constitutes an important risk for human health …

Single-cell RNA transcriptome helps define the limbal/corneal epithelial stem/early transit amplifying cells and how autophagy affects this population

N Kaplan, J Wang, B Wray, P Patel… - … & visual science, 2019 - iovs.arvojournals.org
Purpose: Single-cell RNA-sequencing (scRNA-seq) was used to interrogate the relatively
rare stem (SC) and early transit amplifying (TA) cell populations in limbal/corneal epithelia …

Aflatoxin B1 promotes autophagy associated with oxidative stress-related PI3K/AKT/mTOR signaling pathway in mice testis

W Huang, Z Cao, J Zhang, Q Ji, Y Li - Environmental Pollution, 2019 - Elsevier
Abstract Aflatoxin B 1 (AFB 1) is a hazard environmental pollutants and the most toxic one of
all the aflatoxins. AFB 1 can cause a serious impairment to testicular development and …

Oxidative and antioxidative stress markers in dry eye disease: A systematic review and meta‐analysis

V Navel, V Sapin, F Henrioux, L Blanchon… - Acta …, 2022 - Wiley Online Library
Purpose To conduct a systematic review and meta‐analysis on the levels of oxidative stress
markers and antioxidants in dry eye disease (DED) compared with healthy subject. Method …

[HTML][HTML] Nickel induces autophagy via PI3K/AKT/mTOR and AMPK pathways in mouse kidney

H Yin, Z Zuo, Z Yang, H Guo, J Fang, H Cui… - Ecotoxicology and …, 2021 - Elsevier
Nickel (Ni), a widely distributed metal, is an important pollutant in the environment. Although
kidney is a crucial target of Ni toxicity, information on autophagy and the potential …

Monoterpenes modulating autophagy: A review study

M Ashrafizadeh, Z Ahmadi… - Basic & Clinical …, 2020 - Wiley Online Library
From the beginning of the 21st century, much attention has been made towards the
medicinal herbs due to their low side effects and valuable biological activities. Among them …