[HTML][HTML] Fixel-based analysis of diffusion MRI: methods, applications, challenges and opportunities

T Dhollander, A Clemente, M Singh, F Boonstra… - Neuroimage, 2021 - Elsevier
Diffusion MRI has provided the neuroimaging community with a powerful tool to acquire in-
vivo data sensitive to microstructural features of white matter, up to 3 orders of magnitude …

[HTML][HTML] Investigating white matter fibre density and morphology using fixel-based analysis

DA Raffelt, JD Tournier, RE Smith, DN Vaughan… - Neuroimage, 2017 - Elsevier
Voxel-based analysis of diffusion MRI data is increasingly popular. However, most white
matter voxels contain contributions from multiple fibre populations (often referred to as …

Fibre-specific white matter reductions in Alzheimer's disease and mild cognitive impairment

R Mito, D Raffelt, T Dhollander, DN Vaughan… - Brain, 2018 - academic.oup.com
Alzheimer's disease is increasingly considered a large-scale network disconnection
syndrome, associated with progressive aggregation of pathological proteins, cortical …

[HTML][HTML] Recent advances in diffusion neuroimaging: applications in the developing preterm brain

D Pecheva, C Kelly, J Kimpton, A Bonthrone… - …, 2018 - ncbi.nlm.nih.gov
Measures obtained from diffusion-weighted imaging provide objective indices of white
matter development and injury in the developing preterm brain. To date, diffusion tensor …

[HTML][HTML] Connectivity-based fixel enhancement: Whole-brain statistical analysis of diffusion MRI measures in the presence of crossing fibres

DA Raffelt, RE Smith, GR Ridgway, JD Tournier… - Neuroimage, 2015 - Elsevier
In brain regions containing crossing fibre bundles, voxel-average diffusion MRI measures
such as fractional anisotropy (FA) are difficult to interpret, and lack within-voxel single fibre …

Apparent fibre density: a novel measure for the analysis of diffusion-weighted magnetic resonance images

D Raffelt, JD Tournier, S Rose, GR Ridgway… - Neuroimage, 2012 - Elsevier
This article proposes a new measure called Apparent Fibre Density (AFD) for the analysis of
high angular resolution diffusion-weighted images using higher-order information provided …

Reduced white matter fiber density in autism spectrum disorder

D Dimond, M Schuetze, RE Smith, T Dhollander… - Cerebral …, 2019 - academic.oup.com
Differences in brain networks and underlying white matter abnormalities have been
suggested to underlie symptoms of autism spectrum disorder (ASD). However, robustly …

[HTML][HTML] Differentiation of Alzheimer's disease based on local and global parameters in personalized Virtual Brain models

J Zimmermann, A Perry, M Breakspear, M Schirner… - NeuroImage: Clinical, 2018 - Elsevier
Alzheimer's disease (AD) is marked by cognitive dysfunction emerging from
neuropathological processes impacting brain function. AD affects brain dynamics at the local …

[HTML][HTML] Mahalanobis distance tractometry (MaD-Tract)–a framework for personalized white matter anomaly detection applied to TBI

JM Guerrero-Gonzalez, B Yeske, GR Kirk, MJ Bell… - NeuroImage, 2022 - Elsevier
Imaging-based quantitative measures from diffusion-weighted MRI (dMRI) offer the ability to
non-invasively extract microscopic information from human brain tissues. Group-level …

Same genes, different brains: neuroanatomical differences between monozygotic twins discordant for musical training

Ö de Manzano, F Ullén - Cerebral Cortex, 2018 - academic.oup.com
Numerous cross-sectional and observational longitudinal studies show associations
between expertise and regional brain anatomy. However, since these designs confound …