Cancer cell plasticity defines response to immunotherapy in cutaneous squamous cell carcinoma
L Lorenzo-Sanz, M Lopez-Cerda, V da Silva-Diz… - Nature …, 2024 - nature.com
Immune checkpoint blockade (ICB) approaches have changed the therapeutic landscape for
many tumor types. However, half of cutaneous squamous cell carcinoma (cSCC) patients …
many tumor types. However, half of cutaneous squamous cell carcinoma (cSCC) patients …
Targeting Ferroptosis as an Advance Strategy in Cancer Therapy
TA Muluh, Q Fu, X Ai, C Wang, W Chen… - Antioxidants & Redox …, 2024 - liebertpub.com
Ferroptosis, triggered by the buildup of lipid peroxidation and reliance on iron, is crucial in
maintaining cellular balance. Research related to ferroptosis has surged due to its distinct …
maintaining cellular balance. Research related to ferroptosis has surged due to its distinct …
Immunometabolic characteristics of Dendritic Cells and its significant modulation by mitochondria-associated signaling in the tumor microenvironment influence …
S Ghosh, R Dutta, D Ghatak, D Goswami… - … and Biophysical Research …, 2024 - Elsevier
Dendritic cells (DCs) mediated T-cell responses is critical to anti-tumor immunity. This study
explores immunometabolic attributes of DC, emphasizing on mitochondrial association, in …
explores immunometabolic attributes of DC, emphasizing on mitochondrial association, in …
CIMT 2024: Report on the 21st Annual Meeting of the Association for Cancer Immunotherapy
Y Ahrberg, J Dallmann, J Freitag, A Hassan, C Jung… - 2024 - Taylor & Francis
ABSTRACT The 21st Association for Cancer Immunotherapy (CIMT) Annual Meeting took
place from May 15th to May 17th in Mainz, Germany, and was attended by a total of 855 …
place from May 15th to May 17th in Mainz, Germany, and was attended by a total of 855 …
The tumor microenvironment of VETC+ hepatocellular carcinoma is enriched of immunosuppressive TAMs spatially close to endothelial cells
C De Carlo, R Rosman-Nathanson, B Durante… - Digestive and Liver …, 2024 - Elsevier
Background and aim VETC (vessel that encapsulate tumor cluster) is a peculiar vascular
phenotype observed in hepatocellular carcinoma (HCC), associated with distant metastases …
phenotype observed in hepatocellular carcinoma (HCC), associated with distant metastases …
Ultra-resolution Deconvolution of Spatial Transcriptomics Unveils Spatiotemporal Cellular Dynamics in Complex Microenvironments
Y Xu, Z Huang, Y Zhang, Z Wang, P Guo, F Zhang… - bioRxiv, 2024 - biorxiv.org
The current challenge in analyzing sequencing-based spatial transcriptomics (ST) is to
precisely resolve the spatial distribution of cell subpopulations with low abundance and …
precisely resolve the spatial distribution of cell subpopulations with low abundance and …