[HTML][HTML] A comprehensive review on modeling aspects of infusion-based drug delivery in the brain

T Yuan, W Zhan, M Terzano, GA Holzapfel, D Dini - Acta Biomaterialia, 2024 - Elsevier
Brain disorders represent an ever-increasing health challenge worldwide. While
conventional drug therapies are less effective due to the presence of the blood-brain barrier …

Elasticity imaging using physics-informed neural networks: Spatial discovery of elastic modulus and Poisson's ratio

A Kamali, M Sarabian, K Laksari - Acta biomaterialia, 2023 - Elsevier
Elasticity imaging is a technique that discovers the spatial distribution of mechanical
properties of tissue using deformation and force measurements under various loading …

Tissue‐scale biomechanical testing of brain tissue for the calibration of nonlinear material models

J Faber, J Hinrichsen, A Greiner, N Reiter… - Current …, 2022 - Wiley Online Library
Brain tissue is one of the most complex and softest tissues in the human body. Due to its
ultrasoft and biphasic nature, it is difficult to control the deformation state during …

Distinguishing poroelasticity and viscoelasticity of brain tissue with time scale

L Su, M Wang, J Yin, F Ti, J Yang, C Ma, S Liu, TJ Lu - Acta Biomaterialia, 2023 - Elsevier
Brain tissue is considered to be biphasic, with approximately 80% liquid and 20% solid
matrix, thus exhibiting viscoelasticity due to rearrangement of the solid matrix and …

[HTML][HTML] Mechanical behavior of the hippocampus and corpus callosum: An attempt to reconcile ex vivo with in vivo and micro with macro properties

G Bertalan, J Becker, H Tzschätzsch, A Morr… - Journal of the …, 2023 - Elsevier
Mechanical properties of brain tissue are very complex and vary with the species, region,
method, and dynamic range, and between in vivo and ex vivo measurements. To reconcile …

[HTML][HTML] Correlating the microstructural architecture and macrostructural behaviour of the brain

M Hoppstädter, D Püllmann, R Seydewitz, E Kuhl… - Acta Biomaterialia, 2022 - Elsevier
The computational simulation of pathological conditions and surgical procedures, for
example the removal of cancerous tissue, can contribute crucially to the future of medicine …

Structural anisotropy vs. mechanical anisotropy: the contribution of axonal fibers to the material properties of brain white matter

F Eskandari, M Shafieian, MM Aghdam… - Annals of biomedical …, 2021 - Springer
Brain's micro-structure plays a critical role in its macro-structure material properties. Since
the structural anisotropy in the brain white matter has been introduced due to axonal fibers …

Curvature-induced cell rearrangements in biological tissues

Y Lou, JF Rupprecht, S Theis, T Hiraiwa… - Physical Review Letters, 2023 - APS
On a curved surface, epithelial cells can adapt to geometric constraints by tilting and by
exchanging their neighbors from apical to basal sides, known as an apico-basal topological …

[HTML][HTML] Cell-induced confinement effects in soft tissue mechanics

D Song, JL Shivers, FC MacKintosh… - Journal of Applied …, 2021 - pubs.aip.org
The mechanical properties of tissues play a critical role in their normal and
pathophysiological functions such as tissue development, aging, injury, and disease …

The effect of large deformation on Poisson's ratio of brain white matter: An experimental study

F Eskandari, Z Rahmani… - Proceedings of the …, 2021 - journals.sagepub.com
A more Accurate description of the mechanical behavior of brain tissue could improve the
results of computational models. While most studies have assumed brain tissue as an …