Owing to specific and compelling gene silencing, RNA interference (RNAi) is expected to
become an essential approach in treating a variety of infectious, hemato-oncological …

Self-assembled peptides and proteins possess tremendous potential as targeted drug
delivery systems and key applications of these well-defined nanostructures reside in anti …

Post‐transcriptional gene silencing targets and degrades mRNA transcripts, silencing the
expression of specific genes. RNA interference technology, using synthetic structurally well …

Highlights•Biopharmaceuticals are complex products gaining importance over small
molecules.•They are highly sensitive and selective with potent therapeutic efficacy.•The …

Metal nanoparticles have been widely used in the treatment of diabetic wounds owing to
their proven antibacterial activity and enhanced wound healing effects. Therefore, in this …

RNA-based therapy is a promising and innovative strategy for cancer treatment. However,
poor stability, immunogenicity, low cellular uptake rate, and difficulty in endosomal escape …

Abstract Background Gastrodiae Rhizoma (Tianma), the dried tuber of Gastrodia elata
Bl.(Orchidaceae), is listed as a top-grade herbal medicine in Shen-nong Ben-ts' ao Jing and …

Ocular neovascularization (NV) plays a central role in the pathogenesis of various ocular
diseases including diabetic retinopathy, age-related macular degeneration, retinoblastoma …

The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas13d system
was adapted as a powerful tool for targeting viral RNA sequences, making it a promising …

Nipah virus (NiV), a zoonotic virus, engenders severe infections with noticeable
complications and deaths in humans and animals. Since its emergence, it is frightening, this …