PURPOSE: Although local excision of rectal cancers is a less morbid alternative to radical
resection, its role as a curative procedure is unclear. The role of adjuvant therapy after local …

In selected patients, local excision of rectal cancer may be an alternative to radical surgery
such as abdominoperineal excision of the rectum or anterior resection. Local excision …

Objective: Determine rates of local excision (LE) over time, and test the hypothesis that LE
carries increased oncologic risks but reduced perioperative morbidity when compared with …

PURPOSE: This study was undertaken for the comparison of local resection for early rectal
carcinomas using transanal endoscopic microsurgery or anterior resection. METHODS: Data …

Objective To evaluate the results of local excision alone for the treatment of rectal cancer,
applying strict selection criteria. Background Data Several retrospective studies have …

Purpose: To evaluate the impact of tumor response; tumor and nodal downstaging; and
cTNM, yTNM (clinical stage after chemoradiation, based on preoperative imaging), and …

OBJECTIVE: Most data on local excisions for rectal cancer are based on retrospective
studies. We review the results of a prospective registry of patients eligible for local excision …

BACKGROUND: After treatment with local excision for TNM stage I low rectal cancer, the risk
of local recurrence is not only high for T2 lesions but also for T1 lesions with features of …

Purpose: In previous studies, local excision was predominantly established for “low-risk” pT1
rectal cancer. The results obtained with T2 tumors are unclear; recurrence rates of 0 to 67 …

Background: Local excision of rectal cancer preserves anal continence, bladder function,
and normal sexual function. However, local recurrence after excision remains a significant …