To improve the quality control of drugs, we predicted the absorption, distribution,
metabolism, excretion, and toxicity (ADMET) of ceftazidime (CAZ) and its impurities via in …

The human immunodeficiency virus (HIV) infection and the associated acquired immune
deficiency syndrome (AIDS) remain global challenges even after decades of successful …

Five compounds were synthesized and tested as in vitro against two different cancer cell
lines to find out their antiproliferative activities. The results showed that a compound …

Abstract Development of drug resistance in P. falciparum is one of the major problems
associated with malaria treatment. Parasite genetic factors such as single nucleotide …

The current research involves the synthesis of a new Schiff base through the reaction
between 2-chlorobenzaldehyde and 3, 3′-dimethyl-[1, 1′-biphenyl]-4, 4′-diamine by …

Background: Discovery of novel antimicrobial agents is in need to deal with antibiotic
resistance. Elucidating the mechanism of action for established drugs contributes to this …

As compared to standard medicinal compounds, hybrid molecules that contain multiple
biologically active functional groups have greater affinity and efficiency. Hence based on this …

Macrolide antibiotics (macrolides) are among the most commonly prescribed antibiotics
worldwide and are used for a wide range of infections, but macrolides also expose people to …

In here, a series of pyrimidin-(1 (2 H)-yl) acetamide and pyrimidin-(1 (2 H)-yl) isophthalimide
derivatives were synthesised according to literature. The cytotoxic activity properties of these …

Cancer is a global public health problem that affects millions each year. Novel anticancer
drug candidates are in need to treat various cancers and to overcome the resistance that …