Designing microbial cell factories for the production of chemicals
The sustainable production of chemicals from renewable, nonedible biomass has emerged
as an essential alternative to address pressing environmental issues arising from our heavy …
as an essential alternative to address pressing environmental issues arising from our heavy …
Metabolic engineering strategies to enable microbial utilization of C1 feedstocks
W Jiang, D Hernández Villamor, H Peng… - Nature Chemical …, 2021 - nature.com
Abstract One-carbon (C1) substrates are preferred feedstocks for the biomanufacturing
industry and have recently gained attention owing to their natural abundance, low …
industry and have recently gained attention owing to their natural abundance, low …
Cell-free chemoenzymatic starch synthesis from carbon dioxide
T Cai, H Sun, J Qiao, L Zhu, F Zhang, J Zhang, Z Tang… - Science, 2021 - science.org
Starches, a storage form of carbohydrates, are a major source of calories in the human diet
and a primary feedstock for bioindustry. We report a chemical-biochemical hybrid pathway …
and a primary feedstock for bioindustry. We report a chemical-biochemical hybrid pathway …
Synthetic biology strategies for microbial biosynthesis of plant natural products
Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …
[HTML][HTML] Renewable methanol and formate as microbial feedstocks
Highlights•One-carbon compounds can be made from CO 2 to provide renewable microbial
feedstocks.•Methanol and formate have key advantages over gaseous one-carbon …
feedstocks.•Methanol and formate have key advantages over gaseous one-carbon …
Physiological limitations and opportunities in microbial metabolic engineering
J Montaño López, L Duran, JL Avalos - Nature Reviews Microbiology, 2022 - nature.com
Metabolic engineering can have a pivotal role in increasing the environmental sustainability
of the transportation and chemical manufacturing sectors. The field has already developed …
of the transportation and chemical manufacturing sectors. The field has already developed …
Light-driven CO2 sequestration in Escherichia coli to achieve theoretical yield of chemicals
CO2 sequestration engineering is an attractive strategy for achieving carbon-and energy-
efficient bioproduction. However, the efficiency of heterotrophic CO2 sequestration is limited …
efficient bioproduction. However, the efficiency of heterotrophic CO2 sequestration is limited …
Escherichia coli as a host for metabolic engineering
Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …
earth. Features such as genetic tractability, favorable growth conditions, well characterized …
Industrial biomanufacturing: the future of chemical production
BACKGROUND Environmental, geopolitical, and economic factors are reshaping our view
of global energy and manufacturing demands. Addressing these challenges may require a …
of global energy and manufacturing demands. Addressing these challenges may require a …
Reprogramming methanol utilization pathways to convert Saccharomyces cerevisiae to a synthetic methylotroph
Methanol, an organic one-carbon (C1) compound, represents an attractive alternative
carbon source for microbial fermentation. Despite considerable advancements in methanol …
carbon source for microbial fermentation. Despite considerable advancements in methanol …