Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …

Background and Purpose—The authors present an overview of the current evidence and
management recommendations for evaluation and treatment of adults with acute ischemic …

Despite the enormous progress in the understanding of the course of the ischemic stroke
over the last few decades, a therapy that effectively protects neurovascular units (NVUs) and …

Review on the time-dependent recruitment of inflammatory cells and unanswered questions
regarding inflammatory cells in the pathophysiology of ischemic stroke. Inflammation plays …

Neutrophils are rapidly recruited in response to local tissue infection or inflammation. Stroke
triggers a strong inflammatory reaction but the relevance of neutrophils in the ischemic brain …

Inflammation plays an important role in the pathogenesis of ischemic stroke and other forms
of ischemic brain injury. Increasing evidence suggests that inflammatory response is a …

Context Goal-directed resuscitation for severe sepsis and septic shock has been reported to
reduce mortality when applied in the emergency department. Objective To test the …

Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …