Orofacial clefts (OFCs) rank as the second most common congenital birth defect in the
United States after Down syndrome and are the most common head and neck congenital …

Objective. The exact shape of the dose‐response relationship between maternal body mass
index (BMI) and the risk of congenital heart defects (CHDs) in infants has not been clearly …

Patau Syndrome - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe
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The objective of this study was to examine a large institutional experience of patients with
trisomy 13 and trisomy 18 in the setting of comorbid congenital heart disease and present …

Importance Patient-centered care (PCC) has been advocated by the Institute of Medicine to
improve health care in the United States. Four concepts of PCC align with clinical ethics …

Congenital heart disease (CHD) is the most common of congenital cardiovascular
malformations associated with birth defects, and it results in significant morbidity and …

Management of children with trisomy 13 (T13) is controversial because of a paucity of
evidence of the natural history, especially focusing on efficacy of treatment. There has been …

Microphthalmia, anophthalmia, and coloboma (MAC) are a heterogeneous spectrum of
anomalous eye development and degeneration with genetic and environmental etiologies …

OBJECTIVE: To review the relationship between congenital heart defects and chromosomal
abnormalities detected by the karyotype. DATA SOURCES: Scientific articles were searched …

Individuals with trisomic conditions like Down syndrome and Edwards syndrome are prone
to certain types of malignancy. However, for Patau syndrome (constitutional trisomy 13) …