The respiratory epithelium provides a physical, functional, and immunologic barrier to
protect the host from the potential harming effects of inhaled environmental particles and to …

Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …

Asthma is one of the most common respiratory disease that affects both children and adults
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …

Airway epithelial barrier dysfunction is frequently observed in asthma and may have
important implications. The physical barrier function of the airway epithelium is tightly …

Respiratory viral infections are the most important triggers of asthma exacerbations.
Rhinovirus (RV), the common cold virus, is clearly the most prevalent pathogen constantly …

Allergic bronchial asthma is a chronic disease of the airways that is characterized by
symptoms like respiratory distress, chest tightness, wheezing, productive cough, and acute …

The nasal cellular epigenome may serve as biomarker of airway disease and environmental
response. Here we collect nasal swabs from the anterior nares of 547 children (mean-age …

Bronchiolitis is the most common lower respiratory infection in infants, yet its pathobiology
remains unclear. Here we present blood DNA methylation data from 625 infants hospitalized …

Increase of allergic conditions has occurred at the same pace with the Great Acceleration,
which stands for the rapid growth rate of human activities upon earth from 1950s. Changes …

In asthma and allergy genetics, a trend towards a few main topics developed over the last 2
years. First, a number of studies have been published recently which focus on overlapping …