Abstract Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following
ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate …

The neural crest (NC) is a transient, multipotent and migratory cell population that generates
an astonishingly diverse array of cell types during vertebrate development. These cells …

Schwann cell precursors (SCPs) are nerve‐associated progenitors that can generate
myelinating and non‐myelinating Schwann cells but also are multipotent like the neural …

The neural crest is a multipotent, migratory cell population that is unique to vertebrate
embryos and gives rise to many derivatives, ranging from the peripheral nervous system to …

Interactions between developmental signaling pathways govern the formation and function
of stem cells. Prostaglandin (PG) E2 regulates vertebrate hematopoietic stem cells (HSC) …

Wnt signaling is one of a handful of powerful signaling pathways that play crucial roles in the
animal life by controlling the genetic programs of embryonic development and adult …

In contrast to mammals, lower vertebrates have a remarkable capacity to regenerate
complex structures damaged by injury or disease. This process, termed epimorphic …

The embryonic head is populated by two robust mesenchymal populations, paraxial
mesoderm and neural crest cells. Although the developmental histories of each are distinct …

The Ryk receptor belongs to the atypical receptor tyrosine kinase family. It is a new member
of the family of Wnt receptor proteins. However, the molecular mechanisms by which the Ryk …

The creation of molecular tools able to unravel in vivo spatiotemporal activation of specific
cell signaling events during cell migration, differentiation and morphogenesis is of great …