Bmp4 Is Essential for the Formation of the Vestibular Apparatus that Detects Angular Head Movements

W Chang, Z Lin, H Kulessa, J Hebert, BLM Hogan… - PLoS …, 2008 - journals.plos.org
Angular head movements in vertebrates are detected by the three semicircular canals of the
inner ear and their associated sensory tissues, the cristae. Bone morphogenetic protein 4 …

Induction and segregation of the vertebrate cranial placodes

BY Park, JP Saint-Jeannet - 2010 - books.google.com
During evolution the vertebrate head has acquired a number of unique features including
specialized paired sense organs and cranial sensory ganglia. These evolutionary novelties …

Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons

K Kala, M Haugas, K Lilleväli, J Guimera, W Wurst… - 2009 - journals.biologists.com
Midbrain GABAergic neurons control several aspects of behavior, but regulation of their
development and diversity is poorly understood. Here, we further refine the midbrain regions …

The heterogeneity of mammalian utricular cells over the course of development

D You, J Guo, Y Zhang, L Guo, X Lu… - Clinical and …, 2022 - Wiley Online Library
Background The inner ear organ is a delicate tissue consisting of hair cells (HCs) and
supporting cells (SCs). The mammalian inner ear HCs are terminally differentiated cells that …

Tfap2a promotes specification and maturation of neurons in the inner ear through modulation of Bmp, Fgf and notch signaling

H Kantarci, RK Edlund, AK Groves, BB Riley - PLoS genetics, 2015 - journals.plos.org
Neurons of the statoacoustic ganglion (SAG) transmit auditory and vestibular information
from the inner ear to the hindbrain. SAG neuroblasts originate in the floor of the otic vesicle …

Collective cell migration of the nephric duct requires FGF signaling

L Attia, J Schneider, R Yelin… - Developmental …, 2015 - Wiley Online Library
Background: During the course of development, the vertebrate nephric duct (ND) extends
and migrates from the place of its initial formation, adjacent to the anterior somites, until it …

Expression of the Gata3 transcription factor in the acoustic ganglion of the developing avian inner ear

JM Jones, ME Warchol - Journal of Comparative Neurology, 2009 - Wiley Online Library
During the development of the inner ear, auditory and vestibular ganglion neurons are
generated in a highly regulated sequential process. First, neuroblasts are specified …

Notch and Hedgehog in the thymus/parathyroid common primordium: Crosstalk in organ formation

M Figueiredo, JC Silva, AS Santos, V Proa… - Developmental …, 2016 - Elsevier
The avian thymus and parathyroids (T/PT) common primordium derives from the endoderm
of the third and fourth pharyngeal pouches (3/4PP). The molecular mechanisms that govern …

Defects in sensory organ morphogenesis and generation of cochlear hair cells in Gata3-deficient mouse embryos

M Haugas, K Lilleväli, M Salminen - Hearing research, 2012 - Elsevier
The development of the inner ear sensory epithelia involves a complex network of
transcription factors and signaling pathways and the whole process is not yet entirely …

Slits and Robos in the developing chicken inner ear

AC Battisti, DM Fekete - Developmental Dynamics, 2008 - Wiley Online Library
Mechanosensory hair cells in the chick inner ear synapse onto afferent neurons of the
statoacoustic ganglion (SAG). During development, these neurons extend a central process …